2. Cell Cycle/DNA Damage Metabolic Enzyme/Protease
  3. DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Endogenous Metabolite
  4. Deoxycytidine triphosphate trisodium salt

Deoxycytidine triphosphate trisodium salt  (Synonyms: dCTP trisodium salt; 2′-Deoxycytidine-5′-triphosphate trisodium salt)

Cat. No.: HY-101400A Purity: ≥99.0%
COA Handling Instructions

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Deoxycytidine triphosphate trisodium salt (dCTP trisodium salt) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate trisodium salt has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

For research use only. We do not sell to patients.

Deoxycytidine triphosphate trisodium salt Chemical Structure

Deoxycytidine triphosphate trisodium salt Chemical Structure

CAS No. : 109909-44-6

Size Price Stock Quantity
Solvent
10mg (100 mM * 187.58 μL in Water) USD 50 In-stock
Solvent
25mg (100 mM * 468.95 μL in Water) USD 95 In-stock
Solvent
50mg (100 mM * 937.91 μL in Water) USD 150 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Deoxycytidine triphosphate trisodium salt:

Deoxycytidine triphosphate trisodium salt Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Deoxycytidine triphosphate trisodium salt

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Deoxycytidine triphosphate trisodium salt (dCTP trisodium salt) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate trisodium salt has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing[1][2][3].

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

Assays of thirteen cell lines, derived from mouse lymphomas, myelomas, myeloid tumors, and a mastocytoma, for sensitivity to growth inhibition by 1-β-D-arabinofuranosylcytosine (ara-C) revealed a spectrum between the most and least sensitive which differed 100-fold from each other. An inverse correlation between sensitivity and cellular Deoxycytidine triphosphate (2′-Deoxycytidine-5′-triphosphate, dCTP) content is found, and this suggested that sensitivity of cells might be increased if the dCTP content was lowered during cell exposure to ara-C[1].
? Deoxycytidine triphosphate trisodium salt is a phosphoethanolamine cytidylyltransferase substrate[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Deoxycytidine triphosphate trisodium salt Related Antibodies
Molecular Weight

533.10

Formula

C9H13N3Na3O13P3
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

O[C@H]([C@H](O1)COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O)C[C@@H]1N2C=CC(N)=NC2=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Solution, -20°C, 2 years
Solvent & Solubility
In Vitro: 

H2O : 250 mg/mL (468.96 mM; Need ultrasonic)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (187.58 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥99.0%

COA (248 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.8758 mL 9.3791 mL 18.7582 mL 46.8955 mL
5 mM 0.3752 mL 1.8758 mL 3.7516 mL 9.3791 mL
10 mM 0.1876 mL 0.9379 mL 1.8758 mL 4.6896 mL
15 mM 0.1251 mL 0.6253 mL 1.2505 mL 3.1264 mL
20 mM 0.0938 mL 0.4690 mL 0.9379 mL 2.3448 mL
25 mM 0.0750 mL 0.3752 mL 0.7503 mL 1.8758 mL
30 mM 0.0625 mL 0.3126 mL 0.6253 mL 1.5632 mL
40 mM 0.0469 mL 0.2345 mL 0.4690 mL 1.1724 mL
50 mM 0.0375 mL 0.1876 mL 0.3752 mL 0.9379 mL
60 mM 0.0313 mL 0.1563 mL 0.3126 mL 0.7816 mL
80 mM 0.0234 mL 0.1172 mL 0.2345 mL 0.5862 mL
100 mM 0.0188 mL 0.0938 mL 0.1876 mL 0.4690 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Deoxycytidine triphosphate trisodium salt Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Deoxycytidine triphosphate trisodium109909-44-6dCTP trisodium2′-Deoxycytidine-5′-triphosphate trisodiumDNA/RNA SynthesisNucleoside Antimetabolite/AnalogEndogenous MetabolitepyrimidinecytosineDNAsynthesisnucleosideInhibitorinhibitorinhibit

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