Deoxycytidine triphosphate trisodium,100 mM Solution,PCR Grade
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Deoxycytidine triphosphate (dCTP; 2′-Deoxycytidine-5′-triphosphate) trisodium,100 mM Solution,PCR Grade is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate trisodium,100 mM Solution,PCR Grade has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing. This product is supplied as an aqueous solution.
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- Reinheit: 99.0%
- CAS. Nr.: 109909-44-6
- Formel: C9H13N3Na3O13P3
- Molecular Weight:533.10
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Speicherung:
Solution, -20°C, 2 years
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
Assays of thirteen cell lines, derived from mouse lymphomas, myelomas, myeloid tumors, and a mastocytoma, for sensitivity to growth inhibition by 1-β-D-arabinofuranosylcytosine (ara-C) revealed a spectrum between the most and least sensitive which differed 100-fold from each other. An inverse correlation between sensitivity and cellular Deoxycytidine triphosphate (2′-Deoxycytidine-5′-triphosphate, dCTP) content is found, and this suggested that sensitivity of cells might be increased if the dCTP content was lowered during cell exposure to ara-C[1].
Deoxycytidine triphosphate trisodium,100 mM Solution,PCR Grade is a phosphoethanolamine cytidylyltransferase substrate[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 109909-44-6
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Appearance Liquid
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Molecular Weight 533.10
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Formel C9H13N3Na3O13P3
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Color Colorless to light yellow
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SMILES
O[C@H]1C[C@H](N2C(N=C(N)C=C2)=O)O[C@@H]1COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O
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Synonyms
dCTP trisodium,100 mM Solution,PCR Grade; 2′-Deoxycytidine-5′-triphosphate trisodium,100 mM Solution,PCR Grade
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Solution, -20°C, 2 years
Reinheit & Dokumentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. M H Tattersall, et al. Deoxyribonucleoside triphosphates in human cells: changes in disease and following exposure to drugs. Eur J Clin Invest. 1975 Apr;5(2):191-202. [Content Brief]
[2]. A W Harris, et al. Effect of thymidine on the sensitivity of cultured mouse tumor cells to 1-beta-D-arabinofuranosylcytosine. Cancer Res. 1979 Feb;39(2 Pt 1):538-41. [Content Brief]
[3]. B A Bladergroen, et al. CTP:phosphoethanolamine cytidylyltransferase. Biochim Biophys Acta. 1997 Sep 4;1348(1-2):91-9. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
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