1. Anti-infection
  2. Fungal
  3. FR179642

FR179642 is a key intermediate in the synthesis of the echinocandin antifungal Micafungin. FR179642 is the cyclic peptide nucleus of the echinocandin-like antifungal lipopeptide FR901379.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

FR179642 Chemical Structure

FR179642 Chemical Structure

CAS No. : 168110-44-9

Size Price Stock Quantity
50 mg USD 80 In-stock
100 mg USD 130 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

FR179642 is a key intermediate in the synthesis of the echinocandin antifungal Micafungin[1]. FR179642 is the cyclic peptide nucleus of the echinocandin-like antifungal lipopeptide FR901379[2].

Molecular Weight

936.89

Formula

C35H52N8O20S

CAS No.
Appearance

Solid

Color

White to off-white

Structure Classification
Initial Source

Coleophoma empetri

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (106.74 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.0674 mL 5.3368 mL 10.6736 mL
5 mM 0.2135 mL 1.0674 mL 2.1347 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (106.74 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.0674 mL 5.3368 mL 10.6736 mL 26.6840 mL
5 mM 0.2135 mL 1.0674 mL 2.1347 mL 5.3368 mL
10 mM 0.1067 mL 0.5337 mL 1.0674 mL 2.6684 mL
15 mM 0.0712 mL 0.3558 mL 0.7116 mL 1.7789 mL
20 mM 0.0534 mL 0.2668 mL 0.5337 mL 1.3342 mL
25 mM 0.0427 mL 0.2135 mL 0.4269 mL 1.0674 mL
30 mM 0.0356 mL 0.1779 mL 0.3558 mL 0.8895 mL
40 mM 0.0267 mL 0.1334 mL 0.2668 mL 0.6671 mL
50 mM 0.0213 mL 0.1067 mL 0.2135 mL 0.5337 mL
60 mM 0.0178 mL 0.0889 mL 0.1779 mL 0.4447 mL
80 mM 0.0133 mL 0.0667 mL 0.1334 mL 0.3336 mL
100 mM 0.0107 mL 0.0534 mL 0.1067 mL 0.2668 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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FR179642 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
FR179642
Cat. No.:
HY-129077
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