1. Recombinant Proteins
  2. Cytokines and Growth Factors
  3. Angiopoietins
  4. Angiopoietin Like 2
  5. ANGPTL2/Angiopoietin-like 2 Protein, Human (HEK293, His)

ANGPTL2/Angiopoietin-like 2 Protein, Human (HEK293, His)

Cat. No.: HY-P75577
Handling Instructions

ANGPTL2/angiopoietin-like 2 protein takes center stage as it induces endothelial cell sprouting through dual autocrine and paracrine mechanisms. This ability underscores its critical role in angiogenesis, where balanced signaling events control the formation of new blood vessels. ANGPTL2/Angiopoietin-like 2 Protein, Human (HEK293, His) is the recombinant human-derived ANGPTL2/Angiopoietin-like 2 protein, expressed by HEK293 , with N-His labeled tag. The total length of ANGPTL2/Angiopoietin-like 2 Protein, Human (HEK293, His) is 249 a.a., with molecular weight of ~31.4 kDa.

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Description

ANGPTL2/angiopoietin-like 2 protein takes center stage as it induces endothelial cell sprouting through dual autocrine and paracrine mechanisms. This ability underscores its critical role in angiogenesis, where balanced signaling events control the formation of new blood vessels. ANGPTL2/Angiopoietin-like 2 Protein, Human (HEK293, His) is the recombinant human-derived ANGPTL2/Angiopoietin-like 2 protein, expressed by HEK293 , with N-His labeled tag. The total length of ANGPTL2/Angiopoietin-like 2 Protein, Human (HEK293, His) is 249 a.a., with molecular weight of ~31.4 kDa.

Background

ANGPTL2/Angiopoietin-like 2 protein takes center stage as it exerts its influence on endothelial cells by inducing sprouting through a dual mechanism of autocrine and paracrine action. The protein's capacity to instigate sprouting underscores its pivotal role in angiogenic processes, where the intricate balance of signaling events governs the formation of new blood vessels. By operating both as an autocrine and paracrine factor, ANGPTL2 plays a crucial role in modulating endothelial cell behavior, contributing to the dynamic and coordinated responses essential for angiogenesis. This multifaceted action positions ANGPTL2 as a key player in the complex regulatory network that orchestrates vascular sprouting, highlighting its significance in the intricate processes of tissue vascularization.

Species

Human

Source

HEK293

Tag

N-His

Accession

Q9UKU9 (D245-H493)

Gene ID
Molecular Construction
N-term
His
ANGPTL2 (D245-H493)
Accession # Q9UKU9
C-term
Synonyms
Angiopoietin-related protein 2; ANGPTL2; ANGRP2; ARP2HARP; MGC8889
Molecular Weight

Approximately 31.4 kDa

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

ANGPTL2/Angiopoietin-like 2 Protein, Human (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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ANGPTL2/Angiopoietin-like 2 Protein, Human (HEK293, His)
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HY-P75577
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