Thymine Nucleotide
3'-O-(2-Nitrobenzyl)-dTTP
Cat. No.: HY-185274
CAS No.: 219607-49-5
- Formula: C17H22N3O16P3
- Molecular Weight: 617.29
3'-O-(2-Nitrobenzyl)-dTTP acts as a reversible terminator for DNA chain elongation. 3'-O-(2-Nitrobenzyl)-dTTP interacts with 9°N polymerase (exo-) A485L/Y409V, gets recognized and incorporated into the elongating DNA chain, thereby temporarily terminating the polymerase reaction. 3'-O-(2-Nitrobenzyl)-dTTP carries a 3'-O-(2-nitrobenzyl) blocking group, which can be removed by laser irradiation to regenerate the free 3'-OH− group and restore polymerase activity. 3'-O-(2-Nitrobenzyl)-dTTP is applicable in DNA sequencing studies.
3'-Amino-2',3'-dideoxy-TTP
Cat. No.: HY-171576
CAS No.: 90053-16-0
- Formula: C10H18N3O13P3
- Molecular Weight: 481.18
3'-Amino-2',3'-dideoxy-TTP is a thymidine triphosphate (TTP) derivative. 3'-Amino-2',3'-dideoxy-TTP can act as a chain terminator in DNA synthesis.
