Cytidine 5'-monophosphate
Based on 1 publication(s) in Google Scholar
Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group.
For research use only. We do not sell to patients.
- Purity: 99.82%
- CAS No.: 63-37-6
- Formula: C9H14N3O8P
- Molecular Weight:323.20
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Publications Citing Use of MedChemExpress (MCE) Cytidine 5'-monophosphate
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Bio/Physico-chemical Assay
All Endogenous Metabolite Isoforms
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Biological Activity
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Human Endogenous Metabolite |
Microbial Metabolite |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CCRF-CEM | IC50 |
0.1 μM
Compound: 7
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In vitro cytotoxicity of compounds were determined on Inhibition of human leukemia cell line(CCRF-CEM).
In vitro cytotoxicity of compounds were determined on Inhibition of human leukemia cell line(CCRF-CEM).
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[PMID: 8917645] |
| L1210 | ED50 |
0.05 μM
Compound: ara-CMP
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In vitro cytotoxicity with cleavage by phosphodiesterase-I concentration for 50% loss of viability was determined at 72 hours.
In vitro cytotoxicity with cleavage by phosphodiesterase-I concentration for 50% loss of viability was determined at 72 hours.
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[PMID: 3968680] |
| L1210 | IC50 |
0.41 μM
Compound: ara-CMP
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Inhibitory concentration on multidrug-resistant L1210 leukemia cells.
Inhibitory concentration on multidrug-resistant L1210 leukemia cells.
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[PMID: 1906107] |
| L1210 | IC50 |
0.43 μM
Compound: ara-CMP
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Inhibitory concentration on parentral (sensitive) L1210 leukemia cells.
Inhibitory concentration on parentral (sensitive) L1210 leukemia cells.
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[PMID: 1906107] |
Cytidine 5'-monophosphate is the drug intermediate for synthesis of nucleotide derivatives, that can be used in food and pharmaceutical industries[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 63-37-6
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Appearance Solid
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Molecular Weight 323.20
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Formula C9H14N3O8P
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Color White to off-white
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SMILES
NC(C=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(O)(O)=O)O2)=NC1=O
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Synonyms
5'-Cytidylic acid; 5'-CMP
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Structure Classification
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (1)
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Journal Impact Factor
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Most Recent
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J Pharm Biomed Anal
A novel UHPLC-MS/MS approach for simultaneous quantification of pyrimidine metabolites in human biofluids. [Abstract]2025 Jun 17:265:117026. PMID: 40544701
Cytidine 5'-monophosphate purchased from MedChemExpress. Usage Cited in: J Pharm Biomed Anal. 2025 Jun 17:265:117026. [Abstract]
10 mmol/L ammonium formate and 0.1 % ammonium hydroxide in phase A; 20 mmol/L ammonium formate and 0.1 % ammonium hydroxide in phase B. The interfering compounds are as follows, UMP (9), CMP (10, Cytidine 5'-monophosphate) and TMP (11).
Solvent & Solubility
H2O : 10 mg/mL (30.94 mM; ultrasonic and warming and heat to 60°C)
DMSO : < 1 mg/mL (insoluble or slightly soluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 11.11 mg/mL (34.37 mM); Clear solution; Need ultrasonic and warming and heat to 60°C
Purity & Documentation
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Data Sheet (274 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| H2O | 1 mM | 3.0941 mL | 15.4703 mL | 30.9406 mL | 77.3515 mL |
| 5 mM | 0.6188 mL | 3.0941 mL | 6.1881 mL | 15.4703 mL | |
| 10 mM | 0.3094 mL | 1.5470 mL | 3.0941 mL | 7.7351 mL | |
| 15 mM | 0.2063 mL | 1.0314 mL | 2.0627 mL | 5.1568 mL | |
| 20 mM | 0.1547 mL | 0.7735 mL | 1.5470 mL | 3.8676 mL | |
| 25 mM | 0.1238 mL | 0.6188 mL | 1.2376 mL | 3.0941 mL | |
| 30 mM | 0.1031 mL | 0.5157 mL | 1.0314 mL | 2.5784 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Cytidine 5'-monophosphate Related Classifications
HY-W009162 Related Classifications
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