Adenosine 5'-diphosphate disodium

Name: Adenosine 5'-diphosphate disodium
Brand: MedChemExpress
SKU: HY-D0199
Rating: 4.5 (1 reviews)

Cat. No.: HY-D0199 Purity: 99.66%: FAQs
Data Sheet SDS COA Handling Instructions

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Adenosine 5'-diphosphate disodium is a nucleoside diphosphate. Adenosine 5'-diphosphate disodium is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate disodium is a platelet aggregation agent for hemostasis and the development and extension of arterial thrombosis.

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Adenosine 5'-diphosphate disodium Chemical Structure

CAS No. : 16178-48-6

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Based on 1 publication(s) in Google Scholar

Other Forms of Adenosine 5'-diphosphate disodium:

Adenosine In-stock
Adenosine 5'-diphosphate In-stock
Adenosine 5′-diphosphate-¹⁵N₅ disodium Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target

Human Endogenous Metabolite

In Vitro

Adenosine 5'-diphosphate disodium (10 μmol/L) induces human platelets aggregation and [Ca²⁺]i increasing in platelets, B10 cells, and P2Y1-transfected cells^[1].
Adenosine 5'-diphosphate disodium (5 μmol/L) increases cAMP levels in human platelets and in B10 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

Molecular Weight

471.16

Formula

C₁₀H₁₃N₅Na₂O₁₀P₂

CAS No.

16178-48-6

Appearance

Solid

Color

White to off-white

SMILES

O[C@@H]1[C@H](O)[C@@H](COP(OP(O)(O[Na])=O)(O[Na])=O)O[C@H]1N2C=NC3=C(N)N=CN=C32

Structure Classification

Others

Initial Source

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : 125 mg/mL (265.30 mM; Need ultrasonic)

DMSO : 5 mg/mL (10.61 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.1224 mL	10.6121 mL	21.2242 mL
5 mM	0.4245 mL	2.1224 mL	4.2448 mL
10 mM	0.2122 mL	1.0612 mL	2.1224 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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mg/kg

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.66%

Select Batch:

Data Sheet (276 KB) SDS (393 KB)

COA (253 KB) HNMR (274 KB) CNMR (339 KB) LCMS (95 KB)

Handling Instructions (2659 KB)

References

[1]. Hechler B, et al. The P2Y1 receptor is necessary for adenosine 5'-diphosphate-induced platelet aggregation. Blood. 1998 Jul 1;92(1):152-9. [Content Brief]

[2]. Arts IC, et al. Adenosine 5'-triphosphate (ATP) supplements are not orally bioavailable: a randomized, placebo-controlled cross-over trial in healthy humans. J Int Soc Sports Nutr. 2012 Apr 17;9(1):16. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / H₂O	1 mM	2.1224 mL	10.6121 mL	21.2242 mL	53.0605 mL
	5 mM	0.4245 mL	2.1224 mL	4.2448 mL	10.6121 mL
	10 mM	0.2122 mL	1.0612 mL	2.1224 mL	5.3061 mL
H₂O	15 mM	0.1415 mL	0.7075 mL	1.4149 mL	3.5374 mL
	20 mM	0.1061 mL	0.5306 mL	1.0612 mL	2.6530 mL
	25 mM	0.0849 mL	0.4245 mL	0.8490 mL	2.1224 mL
	30 mM	0.0707 mL	0.3537 mL	0.7075 mL	1.7687 mL
	40 mM	0.0531 mL	0.2653 mL	0.5306 mL	1.3265 mL
	50 mM	0.0424 mL	0.2122 mL	0.4245 mL	1.0612 mL
	60 mM	0.0354 mL	0.1769 mL	0.3537 mL	0.8843 mL
	80 mM	0.0265 mL	0.1327 mL	0.2653 mL	0.6633 mL
	100 mM	0.0212 mL	0.1061 mL	0.2122 mL	0.5306 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.