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Guanosine 5'-triphosphate trisodium salt hydrate

(Synonyms: 5'-GTP trisodium salt hydrate)
9 Cited Publications
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Based on 9 publication(s) in Google Scholar

Guanosine 5'-triphosphate (5'-GTP) trisodium salt hydrate is a G protein (G proteins) signaling activator and a high-energy precursor in the biosynthesis of nucleotide units in DNA and RNA. Guanosine 5'-triphosphate trisodium salt hydrate can promote myogenic cell differentiation by upregulating miRNA (miR133a, miR133b) and myogenic regulatory factor expression, and by inducing human myogenic precursor cells to release exosomes containing guanosine molecules. Guanosine-5'-triphosphate disodium salt hydrate holds promise for research in biosynthesis and skeletal muscle regeneration.

For research use only. We do not sell to patients.

  • Purity: 95.0%
  • CAS No.: 207300-85-4
  • Formula: C10H13N5Na3O14P3·xH2O
  • Storage:

    -20°C, stored under nitrogen, away from moisture

    * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

  • Guanosine 5'-triphosphate trisodium salt hydrate Chemical Structure
    Guanosine 5'-triphosphate trisodium salt hydrate Chemical Structure
  • Experimental Validation Results for Guanosine 5'-triphosphate trisodium salt hydrate
  • Experimental Validation Results for Guanosine 5'-triphosphate trisodium salt hydrate
  • Experimental Validation Results for Guanosine 5'-triphosphate trisodium salt hydrate
  • Experimental Validation Results for Guanosine 5'-triphosphate trisodium salt hydrate
CAS No.: 207300-85-4
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  • Guanosine 5'-triphosphate trisodium salt hydrate Chemical Structure
    Guanosine 5'-triphosphate trisodium salt hydrate Chemical Structure
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    Guanosine 5'-triphosphate trisodium salt hydrate purchased from MedChemExpress. Usage Cited in: J Biol Chem. 2026 Jan 28:111214. [Abstract]

    Customer Validation
     Guanosine 5'-triphosphate trisodium (GTP) (0-100 μM) induced the highest maximum SAMHD1 dNTPase activity.

  • 1/16

    Guanosine 5'-triphosphate trisodium salt hydrate purchased from MedChemExpress. Usage Cited in: J Biol Chem. 2026 Jan 28:111214. [Abstract]

    Customer Validation
     Guanosine 5'-triphosphate trisodium (GTP) (5-1200 μM) effectively induced tetramerization of the recombinant SAMHD1 protein in a dose-dependent manner.

  • 1/16

    Guanosine 5'-triphosphate trisodium salt hydrate purchased from MedChemExpress. Usage Cited in: J Biol Chem. 2026 Jan 28:111214. [Abstract]

    Customer Validation
     High-confidence fits were obtained for the Guanosine 5'-triphosphate trisodium (GTP) (250 μM; 25 min)-activated hydrolysis of dATP.

  • 1/16

    Guanosine 5'-triphosphate trisodium salt hydrate purchased from MedChemExpress. Usage Cited in: J Biol Chem. 2026 Jan 28:111214. [Abstract]

    Customer Validation
     In the absence of competitors, increasing Guanosine 5'-triphosphate trisodium (GTP) (0-50 μM) preincubation concentrations led to increasing activity. Guanosine 5'-triphosphate trisodium (GTP) added at the reaction start further increased SAMHD1 activity.

  • Guanosine 5'-triphosphate trisodium salt hydrate