630-64-8
630-64-8
Chemical Structure
Helveticoside
Synonym(s): Strophanthidin-digitoxoside
- CAS No.: 630-64-8
- Formula:C29H42O9
- Molecular Weight:534.64
InChIKey: QBILRDAMJUPXCX-AGAUEGNUSA-N
SMILES: O=C[C@@]12[C@]3([H])[C@](CC[C@@]1(C[C@H](CC2)O[C@H]4C[C@@H]([C@@H]([C@H](O4)C)O)O)O)([H])[C@@]5([C@](CC3)([C@@H](C(CO6)=CC6=O)CC5)C)O
Biological Activity: Helveticoside (Strophanthidin-digitoxoside) is a helveticosid, possesses an ED50 of 0.17 μM for isolated guinea-pig ileum. Helveticoside has anticancer effect[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Helveticoside | 95.99% | Helveticoside (Strophanthidin-digitoxoside) is a helveticosid, possesses an ED50 of 0.17 μM for isolated guinea-pig ileum. Helveticoside has anticancer effect. | ||||||||||||||||||||
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References
- [1]. K O Haustein, et al. Structure-activity relationship of natural and semi-synthetic genins and glycosides as investigated on the smooth muscle of the guinea-pig ileum. Pharmacology. 1973;10(2):65-75. [Content Brief]
- [2]. An N, et al. Helveticoside Exhibited p53-dependent Anticancer Activity Against Colorectal Cancer. Arch Med Res. 2020 Apr;51(3):224-232. [Content Brief]
