1. Anti-infection
  2. Bacterial
  3. Tunicamycin

Tunicamycin 

Cat. No.: HY-A0098 Purity: 99.69%
Handling Instructions

Tunicamycin, a nucleoside antibiotic and an N-glycosylation inhibitor, causes unfolded protein response and is widely used as pharmacological inducer of endoplasmic reticulum stress. Tunicamycin causes G1 arrest.

For research use only. We do not sell to patients.

Tunicamycin Chemical Structure

Tunicamycin Chemical Structure

CAS No. : 11089-65-9

Size Price Stock Quantity
2 mg USD 190 In-stock
Estimated Time of Arrival: December 31
5 mg USD 385 In-stock
Estimated Time of Arrival: December 31
10 mg USD 650 In-stock
Estimated Time of Arrival: December 31
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Customer Review

Based on 9 publication(s) in Google Scholar

Top Publications Citing Use of Products

    Tunicamycin purchased from MCE. Usage Cited in: Cell Death Dis. 2018 May 22;9(6):604.

    Western blot analysis of ER stress-related proteins after PPI treatment for 48 h in both pH 7.4 and pH 6.5 conditions. Cells treated with Thapsigargin (TG, 0.5 and 1 μM) or Tunicamycin (Tu, 2.5, 5 and 10 μg/mL) for 24 h served as positive controls.

    Tunicamycin purchased from MCE. Usage Cited in: PLoS Biol. 2018 Oct 18;16(10):e2006483. 

    SK-Hep1 cells stably expressing EV or Flag-PGM1 are treated with or without 0.1 ug/mL Tunicamycin, and cell proliferation is measured.
    • Biological Activity

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    Description

    Tunicamycin, a nucleoside antibiotic and an N-glycosylation inhibitor, causes unfolded protein response and is widely used as pharmacological inducer of endoplasmic reticulum stress. Tunicamycin causes G1 arrest[1][2].

    Molecular Weight

    844.94 (n=10)

    Formula

    C₃₉H₆₄N₄O₁₆ (n=₁₀)

    CAS No.

    11089-65-9

    SMILES
    Shipping

    Room temperature in continental US; may vary elsewhere.

    Storage
    Powder -20°C 3 years
    In solvent -80°C 6 months
      -20°C 1 month
    Solvent & Solubility
    In Vitro: 

    DMSO : 40 mg/mL (Need ultrasonic)

    In Vivo:
    • 1.

      Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

      Solubility: ≥ 2 mg/mL (Infinity mM); Clear solution

    • 2.

      Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

      Solubility: ≥ 2 mg/mL (Infinity mM); Clear solution

    • 3.

      Add each solvent one by one:  10% DMSO    90% corn oil

      Solubility: ≥ 2 mg/mL (Infinity mM); Clear solution

    *All of the co-solvents are provided by MCE.
    References

    Purity: 99.69%

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    This equation is commonly abbreviated as: C1V1 = C2V2

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    Keywords:

    TunicamycinBacterialInhibitorinhibitorinhibit

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    Product name:
    Tunicamycin
    Cat. No.:
    HY-A0098
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