1. Anti-infection
  2. Bacterial

Tunicamycin 

Cat. No.: HY-A0098 Purity: 98.00%
Data Sheet SDS Handling Instructions

Tunicamycin is a mixture of homologous nucleoside antibiotics.

For research use only. We do not sell to patients.
Tunicamycin Chemical Structure

Tunicamycin Chemical Structure

CAS No. : 11089-65-9

Size Price Stock Quantity
10 mM * 1 mL in DMSO $242 In-stock
2 mg $60 In-stock
5 mg $110 In-stock
10 mg   Get quote  
50 mg   Get quote  

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Customer Review

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Tunicamycin is a mixture of homologous nucleoside antibiotics. An inhibitor of glycosylation. Tunicamycin Blocks the formation of N-glycosidic linkages by inhibiting the first step in glycoprotein synthesis. In vitro: Tunicamycin causes accumulation of unfolded proteins in cell endoplasmic reticulum (ER). Tunicamycin-induced ER stress suppresses CD44+/CD24- phenotype cell subpopulation. Tunicamycin inhibite invasion, increase cell death, suppress proliferation and reduce migration in the CD44+/CD24- and CD44+/CD24- rich MCF7 cell culture. [1] In vivo: Administering tunicamycin further increase protein expression levels of ER stress indicators and inflammatory cytokines, and resulted in more severe asthma phenotypes in OVALPS-OVA mice. [2]

References
Molecular Weight

844.94 (n=10)

Formula

C₃₉H₆₄N₄O₁₆ (n=₁₀)

CAS No.

11089-65-9

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

10 mM in DMSO

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

Purity: 98.00%

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Tunicamycin
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HY-A0098
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