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  4. ICAM-2/CD102 Immunoglobulin-like Cell Adhesion Molecules
  5. ICAM-2/CD102 Protein, Human (199a.a, HEK293, His)

ICAM-2/CD102 Protein, Human (199a.a, HEK293, His)

Cat. No.: HY-P7775
COA Handling Instructions

CD102 Protein, Human (HEK293, His) is a transmembrane glycoprotein of the immunoglobulin superfamily.

For research use only. We do not sell to patients.

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Size Price Stock Quantity
10 μg $65 In-stock
50 μg $195 In-stock
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Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

  • References


CD102 Protein, Human (HEK293, His) is a transmembrane glycoprotein of the immunoglobulin superfamily.


ICAM-2 (CD102), like the structurally related ICAM-1 (CD54) and ICAM-3 (CD50) proteins is a known ligand for the ß2 family of leukocyte integrins. These include CD11a/CD18 (LFA-1), CD11b/CD18 (Mac-1), and the dendritic cell-specific, ICAM-grabbing non-integrin (DC-SIGN) protein. ICAM-2 harbours two immunoglobulin domains which are homologues to the first and second immunoglobulin domain of ICAM-1 without any known splice variants. ICAM-2 is uniformly present on all subsets of B lymphocyte lineage cells in bone marrow cell suspensions. High level constitutive expression on vascular endothial cells and less responsiveness than ICAM-1 to inflammatory stimuli are also characteristics of ICAM-2. Recombinant ICAM-2 can co-stimulate T cells in vitro. Although ICAM-2 mediates neutrophil transmigration, ICAM-2 appears capable of mediating CD31/PECAM-1-independent leukocyte transmigration. ICAM-2 may also regulate angiogenesis via several mechanisms including survival, cell migration, and Rac activation[1][2].








P13598 (K25-Q223)

Gene ID
rHuCD102, His; Intercellular Adhesion Molecule 2; ICAM-2; CD102; ICAM2
AA Sequence


Molecular Weight

Approximately 43 kDa


Greater than 95% as determined by reducing SDS-PAGE.


Lyophilized powder.


Lyophilized after extensive dialysis against PBS, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.


It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Storage & Stability

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.


Room temperature in continental US; may vary elsewhere.

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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ICAM-2/CD102 Protein, Human (199a.a, HEK293, His)
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