ICAM-2/CD102 Protein, Human (HEK293, His, solution)

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Based on 1 Customer Validation

ICAM-2/CD102 protein belongs to the ICAM family of the immunoglobulin superfamily and may be involved in immune responses and cell interactions. This is consistent with the family's established role in immune processes. ICAM-2/CD102 Protein, Human (223a.a, HEK293, His) is the recombinant human-derived ICAM-2/CD102 protein, expressed by HEK293 , with C-His labeled tag.

For research use only. We do not sell to patients.
  • Species: Human
  • Source: HEK293
  • Storage:
    Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
  • Biological Activity
  • Technical Parameters
  • Product Properties
  • Documentation
  • Help & FAQs

Biological Activity

Description

ICAM-2/CD102 protein belongs to the ICAM family of the immunoglobulin superfamily and may be involved in immune responses and cell interactions. This is consistent with the family's established role in immune processes. ICAM-2/CD102 Protein, Human (223a.a, HEK293, His) is the recombinant human-derived ICAM-2/CD102 protein, expressed by HEK293 , with C-His labeled tag.

Background

ICAM-2/CD102 protein is a member of the immunoglobulin superfamily and is specifically categorized within the ICAM family. This designation signifies its likely involvement in immune responses and cellular interactions, consistent with the family's established role in immunological processes. As part of the immunoglobulin superfamily, ICAM-2/CD102 may engage in complex interactions contributing to immune regulation. Further exploration is warranted to elucidate the specific functions and implications of ICAM-2/CD102 within the broader context of the immunoglobulin superfamily, shedding light on its role in modulating immune responses and cellular adhesion.

Verified Bioactivity

Measured by the ability of the immobilized protein to support the adhesion of PMA-stimulated HSB2 human peripheral blood acute lymphoblastic leukemia cells.

MCE Validation Data

  • Purity - SDS-PAGE

    Purity - SDS-PAGE

    ≥ 95%, as determined by reducing SDS-PAGE.

Technical Parameters

  • Species Human
  • Source HEK293
  • Tag C-His
  • Accession
  • Gene ID
  • Protein Length

    Extracellular Domain

  • Synonyms

    ICAM2; Intercellular Adhesion Molecule 2, Isoform CRA_a; Intercellular Adhesion Molecule 2; CD102 Antigen; CD102; ICAM2 Protein; ICAM-2

  • AA Sequence

    SDEKVFEVHVRPKKLAVEPKGSLEVNCSTTCNQPEVGGLETSLDKILLDEQAQWKHYLVSNISHDTVLQCHFTCSGKQESMNSNVSVYQPPRQVILTLQPTLVAVGKSFTIECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAPQEATATFNSTADREDGHRNFSCLAVLDLMSRGGNIFHKHSAPKMLEIYEPVSDSQ

  • Predicted Molecular Mass

    24 kDa

  • Molecular Weight

    Approximately 50-55 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.

  • Glycosylation

    Yes

  • Purity

    ≥ 95%, as determined by reducing SDS-PAGE.

Product Properties

Appearance

Solution

Formulation

Supplied as a 0.22 μm filtered solution of PBS, pH 7.5.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Storage & Stability

Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping

Shipping with dry ice.

Calculators

Reconstitution Calculator

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) Volume (to add to vial)
=
Mass (in vial) Mass (in vial)
÷
Desired Reconstitution Concentration Desired Reconstitution Concentration
Dilution Calculator

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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The Specific Activity Calculator Equation
  • Specific Activity (Unit/mg)
  • Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) Specific Activity (Unit/mg)
Unit/mg
= 106 ÷
Biological Activity (ED50) Biological Activity (ED50)
106 ÷
ng/mL
MOQ
Minimum order quantity
100 mg

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