1. GPCR/G Protein
    Immunology/Inflammation
  2. CXCR
  3. SX-682

SX-682 

Cat. No.: HY-119339
Handling Instructions

SX-682 is an orally bioavailable, potent allosteric inhibitor of CXCR1 and CXCR2. SX-682 can block tumor myeloid-derived suppressor cells (MDSCs) recruitment and enhance T cell activation and antitumor immunity.

For research use only. We do not sell to patients.

SX-682 Chemical Structure

SX-682 Chemical Structure

CAS No. : 1648843-04-2

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Description

SX-682 is an orally bioavailable, potent allosteric inhibitor of CXCR1 and CXCR2. SX-682 can block tumor myeloid-derived suppressor cells (MDSCs) recruitment and enhance T cell activation and antitumor immunity[1].

IC50 & Target

CXCR1

 

CXCR2

 

Molecular Weight

467.20

Formula

C₁₉H₁₄BF₄N₃O₄S

CAS No.

1648843-04-2

SMILES

O=C(NC1=CC=C(F)C=C1)C(C=N2)=CN=C2SCC3=CC(OC(F)(F)F)=CC=C3B(O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

SX-682SX682SX 682CXCRCXC chemokine receptorsC-X-C motif chemokine receptorsInhibitorinhibitorinhibit

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