1648843-04-2
1648843-04-2
Chemical Structure
SX-682
- CAS 番号: 1648843-04-2
- Formula:C19H14BF4N3O4S
- Molecular Weight:467.20
IUPAC Name: (2-(((5-((4-fluorophenyl)carbamoyl)pyrimidin-2-yl)thio)methyl)-4-(trifluoromethoxy)phenyl)boronic acid
InChIKey: SDUDZBCEHIZMFZ-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(F)C=C1)C(C=N2)=CN=C2SCC3=CC(OC(F)(F)F)=CC=C3B(O)O
Biological Activity: SX-682 is an orally bioavailable, potent allosteric inhibitor of CXCR1 and CXCR2. SX-682 can block tumor myeloid-derived suppressor cells (MDSCs) recruitment and enhance T cell activation and antitumor immunity[1].
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SX-682 | 99.64% | SX-682 is an orally bioavailable, potent allosteric inhibitor of CXCR1 and CXCR2. SX-682 can block tumor myeloid-derived suppressor cells (MDSCs) recruitment and enhance T cell activation and antitumor immunity. | ||||||||||||||||||||
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References
Keywords
