1. GPCR/G Protein
    Immunology/Inflammation
  2. CXCR

AZD-5069 

Cat. No.: HY-19855 Purity: 98.97%
Handling Instructions

AZD-5069 is a potent CXCR2 chemokine receptor antagonist, used for caner treatment.

For research use only. We do not sell to patients.

AZD-5069 Chemical Structure

AZD-5069 Chemical Structure

CAS No. : 878385-84-3

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 94 In-stock
Estimated Time of Arrival: December 31
1 mg USD 60 In-stock
Estimated Time of Arrival: December 31
5 mg USD 90 In-stock
Estimated Time of Arrival: December 31
10 mg USD 150 In-stock
Estimated Time of Arrival: December 31
25 mg USD 290 In-stock
Estimated Time of Arrival: December 31
50 mg USD 450 In-stock
Estimated Time of Arrival: December 31
100 mg USD 850 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

AZD-5069 is a potent CXCR2 chemokine receptor antagonist, used for caner treatment.

In Vitro

AZD-5069 acts as CXCR2 antagonist by inhibition of [125I]-IL-8 binding to human CXCR2 receptors and as inhibitor of GROα-induced Ca2+ flux in human neutrophils loaded with fluo-3 dye[1].

Clinical Trial
Solvent & Solubility
In Vitro: 

DMSO : ≥ 83.3 mg/mL (174.81 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0985 mL 10.4927 mL 20.9855 mL
5 mM 0.4197 mL 2.0985 mL 4.1971 mL
10 mM 0.2099 mL 1.0493 mL 2.0985 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

476.52

Formula

C₁₈H₂₂F₂N₄O₅S₂

CAS No.

878385-84-3

SMILES

O=S(N1CCC1)(NC2=NC(SCC3=CC=CC(F)=C3F)=NC(O[[email protected]](C)[[email protected]@H](O)CO)=C2)=O

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Inquiry Information

Product Name:
AZD-5069
Cat. No.:
HY-19855
Quantity:

AZD-5069

Cat. No.: HY-19855