2. Signaling Pathways
  3. GPCR/G Protein
    Immunology/Inflammation
  4. CXCR
  5. CXCR2 Isoform
  6. CXCR2 Inhibitor

CXCR2 Inhibitor

CXCR2 Inhibitors (5):

Cat. No. Product Name Effect Purity
  • HY-15251
    Reparixin
    		Inhibitor 99.98%
    Reparixin is a non-competitive allosteric inhibitor of the chemokine receptors CXCR1 and CXCR2 activation with IC50s of 1 and 100 nM, respectively.
  • HY-119339
    SX-682
    		Inhibitor 98.64%
    SX-682 is an orally bioavailable, potent allosteric inhibitor of CXCR1 and CXCR2.
  • HY-15252
    Reparixin L-lysine salt
    		Inhibitor 99.93%
    Reparixin L-lysine salt is a potent and specific allosteric inhibitor of both CXCL8 receptors CXCR1/2, it inhibits weakly CXCR2-mediated cell migration (IC50=100 nM), whereas it strongly blocks CXCR1-mediated chemotaxis (IC50=1 nM).
  • HY-101022
    CXCR2-IN-1
    		Inhibitor 99.47%
    CXCR2-IN-1 is a central nervous system penetrant CXCR2 antagonist with a pIC50 of 9.3.
  • HY-N2573
    Corydalmine
    		Inhibitor
    Corydalmine (L-Corydalmine) inhibits spore germination of some plant pathogenic as well as saprophytic fungi.