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  3. Corydalmine

Corydalmine (Synonyms: L-Corydalmine)

Cat. No.: HY-N2573
Handling Instructions

Corydalmine (L-Corydalmine), an alkaloid isolated from roots of Corydalis Chaerophylla, inhibits spore germination of some plant pathogenic as well as saprophytic fungi. Corydalmine acts as an oral analgesic agent, exhibiting potent analgesic activity. Corydalmine alleviates Vincristine-induced neuropathic pain in mice by inhibiting an NF-κB-dependent CXCL1/CXCR2 signaling pathway.

For research use only. We do not sell to patients.

Corydalmine Chemical Structure

Corydalmine Chemical Structure

CAS No. : 30413-84-4

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Description

Corydalmine (L-Corydalmine), an alkaloid isolated from roots of Corydalis Chaerophylla, inhibits spore germination of some plant pathogenic as well as saprophytic fungi[1]. Corydalmine acts as an oral analgesic agent, exhibiting potent analgesic activity[2]. Corydalmine alleviates Vincristine-induced neuropathic pain in mice by inhibiting an NF-κB-dependent CXCL1/CXCR2 signaling pathway[3].

IC50 & Target[3]

CXCR2

 

In Vivo

Corydalmine (L-Corydalmine) is a potent analgesic agent, in cynomolgus monkey, beagle dog, rat and mouse liver microsomes[2].

Molecular Weight

341.40

Formula

C₂₀H₂₃NO₄

CAS No.

30413-84-4

SMILES

OC1=CC=C2C(CN3CCC4=CC(OC)=C(OC)C=C4[[email protected]]3([H])C2)=C1OC

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

CorydalmineL-CorydalmineFungalCXCRCXC chemokine receptorsC-X-C motif chemokine receptorsInhibitorinhibitorinhibit

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