473728-58-4
473728-58-4
Chemical Structure
SCH 563705
- CAS No.: 473728-58-4
- Formula:C23H27N3O5
- Molecular Weight:425.48
IUPAC Name: (R)-2-hydroxy-3-((2-((1-(4-isopropylfuran-2-yl)propyl)amino)-3,4-dioxocyclobut-1-en-1-yl)amino)-N,N-dimethylbenzamide
InChIKey: DGKQQEVYYPCMNE-OAHLLOKOSA-N
SMILES: O=C(C(NC1=CC=CC(C(N(C)C)=O)=C1O)=C2N[C@H](CC)C3=CC(C(C)C)=CO3)C2=O
Biological Activity: SCH 563705 is a potent and orally available CXCR2 and CXCR1 antagonist, with IC50s of 1.3 nM, 7.3 nM and Kis of 1 and 3 nM, respectively.
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SCH 563705 | 99.86% | SCH 563705 is a potent and orally available CXCR2 and CXCR1 antagonist, with IC50s of 1.3 nM, 7.3 nM and Kis of 1 and 3 nM, respectively. | ||||||||||||||||||||
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SCH 563705 (Standard) | ≥98% | SCH 563705 (Standard) is the analytical standard of SCH 563705 (HY-10011). This product is intended for research and analytical applications. SCH 563705 is a potent and orally available CXCR2 and CXCR1 antagonist, with IC50s of 1.3 nM, 7.3 nM and Kis of 1 and 3 nM, respectively. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 1.00
HY-10011B(Rac)-SCH 563705 -
Similarity Score 0.81
HY-10198Navarixin -
Similarity Score 0.79
HY-162505SQA1 -
Similarity Score 0.74
HY-173491CXCR2/CCR7 antagonist-1 -
Similarity Score 0.51
HY-148531PF-07054894 -
Similarity Score 0.50
HY-173052SLW131 -
Similarity Score 0.44
HY-172587CB1R Allosteric modulator 5 -
Similarity Score 0.42
HY-161104Kv2.1-IN-1 -
Similarity Score 0.42
HY-13017BIvacaftor hydrate -
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