485842-97-5
485842-97-5
Chemical Structure
PMX464
Synonym(s): AW 464
- CAS No.: 485842-97-5
- Formula:C13H9NO2S
- Molecular Weight:243.28
IUPAC Name: 4-(benzo[d]thiazol-2-yl)-4-hydroxycyclohexa-2,5-dien-1-one
InChIKey: SDYBYKXWYDVVKP-UHFFFAOYSA-N
SMILES: O=C1C=CC(O)(C2=NC3=CC=CC=C3S2)C=C1
Biological Activity: PMX464 (AW 464), a thiol-reactive quinol, is the inhibitor of thioredoxin-thioredoxin reductase (Trx/TrxR) system. PMX464 can inhibit NF-κB-mediated proinflammatory activation of human type II alveolar epithelial cells[1].
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PMX464 | PMX464 (AW 464), a thiol-reactive quinol, is the inhibitor of thioredoxin-thioredoxin reductase (Trx/TrxR) system. PMX464 can inhibit NF-κB-mediated proinflammatory activation of human type II alveolar epithelial cells. | |||||||||||||||||||||
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References
Keywords
