2035085-19-7
2035085-19-7
Chemical Structure
BC-1485
- CAS No.: 2035085-19-7
- Formula:C19H21N5O5S
- Molecular Weight:431.47
IUPAC Name: N-(1-(dimethylamino)-1-oxopropan-2-yl)-4-((2-oxo-2,3-dihydro-1H-benzo[d]imidazole)-5-sulfonamido)benzamide
InChIKey: ZDIJTGCDKBHHPD-UHFFFAOYSA-N
SMILES: O=C(NC(C)C(N(C)C)=O)C1=CC=C(NS(=O)(C2=CC=C(N3)C(NC3=O)=C2)=O)C=C1
Biological Activity: BC-1485 is a small molecule inhibitor of Fibrosis-inducing E3 ligase 1 (FIEL1). BC-1485 protects PIAS4 from ubiquitin-mediated degradation. BC-1485 decreases α-SMA, BAL and CXCL1. BC-1485 ameliorates fibrotic lung injury in murine models[1][2].
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BC-1485 | BC-1485 is a small molecule inhibitor of Fibrosis-inducing E3 ligase 1 (FIEL1). BC-1485 protects PIAS4 from ubiquitin-mediated degradation. BC-1485 decreases α-SMA, BAL and CXCL1. BC-1485 ameliorates fibrotic lung injury in murine models. | |||||||||||||||||||||
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References
Keywords
