1. Recombinant Proteins
  2. RANTES/CCL5 Protein, Human (HEK293)

RANTES/CCL5 Protein, Human (HEK293)

Cat. No.: HY-P7282
Handling Instructions

RANTES/CCL5 Protein, Human (HEK293) is a potent CC chemokine, plays an important role in rheumatoid arthritis pathogenesis.

For research use only. We do not sell to patients.

Protein Expression Service

Recombinant Proteins-MedChemExpress
Size Price Stock Quantity
10 μg $135 In-stock
Estimated Time of Arrival: December 31
50 μg $400 In-stock
Estimated Time of Arrival: December 31
100 μg   Get quote  
250 μg   Get quote  

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  • Technical Parameters

  • Properties

  • Documentation

Synonyms
rHuRANTES/CCL5; C-C motif chemokine 5; SCYA5
Species

Human

Source

HEK 293

Accession

P13501 (S24-S91)

Gene ID

6352

Molecular Weight

Approximately 8 kDa

AA Sequence

SPYSSDTTPCCFAYIARPLPRAHIKEYFYTSGKCSNPAVVFVTRKNRQVCANPEKKWVREYINSLEMS

Biological Activity
The ED50 is <0.2 μg/mL as measured by CHO-K1/Gα15/hCCR1 cells (human Gα15 and human CCR1 stably expressed in CHO-K1 cells).
Appearance

Lyophilized powder.

Formulation

Lyophilized after extensive dialysis against PBS.

Endotoxin Level

<0.2 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O or PBS.

Storage & Stability

Stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Background

RANTES/CCL5 is a potent CC chemokine shown to play an important role in rheumatoid arthritis pathogenesis. RANTES/CCL5 primarily attracts lymphocytes and monocytes as well as other cell types. Rheumatoid arthritis synovial fibroblasts produce RANTES/CCL5 upon stimulation with TNF-α, IL-1β, or interferon gamma[1].

Documentation
References
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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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Product Name:
RANTES/CCL5 Protein, Human (HEK293)
Cat. No.:
HY-P7282
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