1. Signaling Pathways
  2. GPCR/G Protein
    Immunology/Inflammation
  3. CCR
  4. CCR2 Inhibitors

CCR2 Inhibitors

CCR1

CCR2

CCR3

CCR4

CCR5

CCR6

CCR7

CCR8

CCR9

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform CCR2 together.

Please try each isoform separately.

CCR2 Specific Antagonists
Product Name CCR2 CCR1 CCR5 CCR2 Selectivity Purity
RS 504393
CCR2, IC50: 89 nM
    Selective Antagonist 99.75%
INCB3344
hCCR2, IC50: 5.1 nM
mCCR2, IC50: 9.5 nM
    Selective Antagonist 99.73%
PF-4136309
Human CCR2, IC50: 5.2 nM
Mouse CCR2, IC50: 13 nM
Rat CCR2, IC50: 17 nM
    Selective Antagonist ≥98.0%
TAK-779
MCP-1-CCR2b, IC50: 27 nM (in CHO/CCR5 cells)
 
MIP-1β-CCR5, IC50: 1 nM (in CHO/CCR5 cells)
RANTES-CCR5, IC50: 1.4 nM (in CHO/CCR5 cells)
MIP-1α-CCR5, IC50: 1 nM (in CHO/CCR5 cells)
Selective Antagonist ≥98.0%
RS102895 hydrochloride
CCR2, IC50: 360 nM
CCR1, IC50: 17800 nM
  Selective Antagonist 99.69%
MK-0812 Succinate
CCR2
    Selective Antagonist 99.69%
CCR2-RA-[R]
CCR2, IC50: 103 nM (in U2OS-CCR2 cells)
    Selective Antagonist 98.41%
INCB 3284
MCP-1-hCCR2, IC50: 3.7 nM
    Selective Antagonist ≥98.0%
CCR2 antagonist 4 hydrochloride
CCR2b, IC50: 180 nM
    Selective Antagonist 99.88%
AZD2423
CCR2
    Selective Antagonist 98.56%
CCR2 antagonist 4
CCR2b, IC50: 180 nM
    Selective Antagonist ≥99.0%
BMS CCR2 22
CCR2, IC50: 5.1 nM
    Selective Antagonist ≥99.0%
CCR2 antagonist 3
CCR2
    Selective Antagonist 98.10%
YM022
CCR2, Ki: 68 pM
CCR1, Ki: 63 nM
  Selective Antagonist ≥99.0%
CCR2 antagonist 1
CCR2, Ki: 2.4 nM
    Selective Antagonist 98.67%
RS102895
CCR2, IC50: 360 nM
CCR1, IC50: 17800 nM
  Selective Antagonist
MK-0812
CCR2
    Selective Antagonist 99.75%
INCB 3284 dimesylate
MCP-1-hCCR2, IC50: 3.7 nM
    Selective Antagonist ≥98.0%
PF-04634817 succinate
Rat CCR2, IC50: 20.8 nM
 
CCR5, IC50: 470 nM
Selective Antagonist ≥99.0%
Cenicriviroc
CCR2, IC50: 5.9 nM
 
CCR5, IC50: 0.29 nM
Pan Antagonist 98.07%
Cenicriviroc Mesylate
CCR2, IC50: 5.9 nM
 
CCR5, IC50: 0.29 nM
Pan Antagonist 98.84%
BMS-813160
CCR2
 
CCR5
Pan Antagonist 99.89%
PF-04634817
Rat CCR2, IC50: 20.8 nM
 
CCR5, IC50: 470 nM
Pan Antagonist 98.87%