2850189-48-7

DOTA-ECL1i Chemical Structure
2850189-48-7

Chemical Structure

DOTA-ECL1i

  • CAS No.: 2850189-48-7
  • Formula:C58H94N14O18S
  • Molecular Weight:1307.51

InChIKey: MUIXJRGBNNZVEY-SQQUKPBYSA-N

SMILES: OC([C@@H](CSC(CC1=O)C(N1CCNC(CN2CCN(CCN(CCN(CC2)CC(O)=O)CC(O)=O)CC(O)=O)=O)=O)NC([C@@H](CCCCN)NC([C@@H](CC(C)C)NC([C@H](NC([C@@H]([C@@H](O)C)NC(CNC([C@H](N)CC(C)C)=O)=O)=O)CC3=CC=CC=C3)=O)=O)=O)=O

Biological Activity: DOTA-ECL1i is a conjugate of the CCR2 inhibitor ECL1i (HY-P11553) and DOTA. When radiolabeled with 68Ga, DOTA-ECL1i serves as a PET tracer that targets CCR2 expression. DOTA-ECL1i can be used in research related to pulmonary fibrosis, cardiac injury, abdominal aortic aneurysm inflammation, atherosclerosis, head and neck cancer, and pancreatic cancer[1].

Cat. No. Product Name Purity Description Pricing
HY-P11553B
DOTA-ECL1i 98.06% DOTA-ECL1i is a conjugate of the CCR2 inhibitor ECL1i (HY-P11553) and DOTA. When radiolabeled with 68Ga, DOTA-ECL1i serves as a PET tracer that targets CCR2 expression. DOTA-ECL1i can be used in research related to pulmonary fibrosis, cardiac injury, abdominal aortic aneurysm inflammation, atherosclerosis, head and neck cancer, and pancreatic cancer.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References