1313730-14-1
1313730-14-1
Chemical Structure
CCR2 antagonist 4 hydrochloride
Synonym(s): Teijin compound 1 hydrochloride
- CAS No.: 1313730-14-1
- Formula:C21H22Cl2F3N3O2
- Molecular Weight:476.32
IUPAC Name: (R)-N-(2-((1-(4-chlorobenzyl)pyrrolidin-3-yl)amino)-2-oxoethyl)-3-(trifluoromethyl)benzamide hydrochloride
InChIKey: PGUQBBISBKGQDC-GMUIIQOCSA-N
SMILES: O=C(NCC(N[C@H]1CN(CC2=CC=C(Cl)C=C2)CC1)=O)C3=CC=CC(C(F)(F)F)=C3.[H]Cl
Biological Activity: CCR2 antagonist 4 hydrochloride (Teijin compound 1 hydrochloride) is a potent and specific CCR2 antagonist, with IC50s of 180 nM for CCR2b. CCR2 antagonist 4 hydrochloride potently inhibits MCP-1-induced chemotaxis with an IC50 of 24 nM[1].
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CCR2 antagonist 4 hydrochloride | 99.91% | CCR2 antagonist 4 hydrochloride (Teijin compound 1 hydrochloride) is a potent and specific CCR2 antagonist, with IC50s of 180 nM for CCR2b. CCR2 antagonist 4 hydrochloride potently inhibits MCP-1-induced chemotaxis with an IC50 of 24 nM. | ||||||||||||||||||||
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