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    Immunology/Inflammation
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  3. BMS-813160

BMS-813160 

Cat. No.: HY-109593 Purity: 99.89%
Handling Instructions

BMS-813160 is the first dual CCR2/CCR5 antagonist, has the potential for cardiovascular treatment.

For research use only. We do not sell to patients.

BMS-813160 Chemical Structure

BMS-813160 Chemical Structure

CAS No. : 1286279-29-5

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 299 In-stock
Estimated Time of Arrival: December 31
2 mg USD 140 In-stock
Estimated Time of Arrival: December 31
5 mg USD 280 In-stock
Estimated Time of Arrival: December 31
10 mg USD 450 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1350 In-stock
Estimated Time of Arrival: December 31
100 mg USD 1950 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

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Description

BMS-813160 is the first dual CCR2/CCR5 antagonist, has the potential for cardiovascular treatment.

IC50 & Target[1]

CCR2

 

CCR5

 

Clinical Trial
Molecular Weight

484.64

Formula

C₂₅H₄₀N₈O₂

CAS No.

1286279-29-5

SMILES

CC(N[[email protected]]1[[email protected]@H](N2C([[email protected]@H](NC3=NC=NC4=CC(C(C)(C)C)=NN43)CC2)=O)CC[[email protected]@H](NC(C)(C)C)C1)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (51.58 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0634 mL 10.3169 mL 20.6339 mL
5 mM 0.4127 mL 2.0634 mL 4.1268 mL
10 mM 0.2063 mL 1.0317 mL 2.0634 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (4.29 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (4.29 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (4.29 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: 99.89%

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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

BMS-813160BMS813160BMS 813160CCRCC chemokine receptorInhibitorinhibitorinhibit

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Product Name:
BMS-813160
Cat. No.:
HY-109593
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