1. Signaling Pathways
  2. GPCR/G Protein
    Immunology/Inflammation
  3. CCR
  4. CCR Inhibitors

CCR Inhibitors

CCR1

CCR2

CCR3

CCR4

CCR5

CCR6

CCR7

CCR8

CCR9

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

CCR Inhibitors, Agonists & Antagonists
Product Name CCR1 CCR2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 Purity
Maraviroc        
MIP-1α-CCR5, IC50: 3.3 nM (in HEK-293 cell membrane)
MIP-1β-CCR5, IC50: 7.2 nM (in HEK-293 cell membrane)
RANTES-CCR5, IC50: 5.2 nM (in HEK-293 cell membrane)
        99.95%
RS 504393  
CCR2, IC50: 89 nM
              99.75%
INCB3344  
hCCR2, IC50: 5.1 nM
mCCR2, IC50: 9.5 nM
              99.73%
PF-4136309  
Human CCR2, IC50: 5.2 nM
Mouse CCR2, IC50: 13 nM
Rat CCR2, IC50: 17 nM
              99.59%
CCR6 antagonist 1          
CCR6
      99.55%
RPT193      
CCR4
         
Mogamulizumab      
CCR4
         
RS102895 hydrochloride
CCR1, IC50: 17800 nM
CCR2, IC50: 360 nM
              99.87%
TAK-779  
MCP-1-CCR2b, IC50: 27 nM (in CHO/CCR5 cells)
   
MIP-1β-CCR5, IC50: 1 nM (in CHO/CCR5 cells)
RANTES-CCR5, IC50: 1.4 nM (in CHO/CCR5 cells)
MIP-1α-CCR5, IC50: 1 nM (in CHO/CCR5 cells)
        99.73%
BX471
MIP-1α-CCR1, Ki: 1 nM
RANTES-CCR1, Ki: 2.8 nM
MCP-3-CCR1, Ki: 5.5 nM
                99.94%
CCR6 inhibitor 1          
Moneky CCR6, IC50: 0.45 nM
Human CCR6, IC50: 6 nM
Human CCR7, IC50: 9400 nM
    99.87%
Cenicriviroc  
CCR2, IC50: 5.9 nM
   
CCR5, IC50: 0.29 nM
        99.01%
AZ084              
CCR8, Ki: 0.9 nM
  99.69%
Vercirnon                
CCR9, IC50: 10 nM
98.19%
INCB 3284  
MCP-1-hCCR2, IC50: 3.7 nM
              99.30%
GW 766994    
CCR3, pKi: 7.86
            99.73%
CCR7 Ligand 1            
Human CCR7, Kd: 3 nM
    99.64%
MK-0812 Succinate  
CCR2
              99.94%
J-113863
CCR1, IC50: 0.9 nM (Human CCR1)
CCR1, IC50: 5.8 nM (Mouse CCR1)
 
CCR3, IC50: 0.58 nM (Human CCR3)
CCR3, IC50: 460 nM (Mouse CCR3)
            ≥99.0%
AZD2098      
CCR4
          99.86%
R243              
CCR8
  98.90%
BX471 hydrochloride
MIP-1α-CCR1, Ki: 1 nM
RANTES-CCR1, Ki: 2.8 nM
MCP-3-CCR1, Ki: 5.5 nM
                99.51%
CCR2 antagonist 4 hydrochloride  
CCR2b, IC50: 180 nM
              99.88%
CCR2-RA-[R]  
CCR2, IC50: 103 nM (in U2OS-CCR2 cells)
              98.41%
DAPTA        
gp120BaL/sCD4-CCR5, IC50: 55 pM (in Cf2Th/synR5 cells)
gp120CMCM235/sCD4-CCR5, IC50: 0.32 nM (in Cf2Th/synR5 cells)
        98.87%
LMD-009              
CCR8, EC50: 11-87 nM
  99.85%
Cenicriviroc Mesylate  
CCR2, IC50: 5.9 nM
   
CCR5, IC50: 0.29 nM
        99.04%
BMS-813160  
CCR2, IC50: 6.2 nM
   
CCR5, IC50: 3.6 nM
        99.89%
ZK756326 dihydrochloride              
CCR8, IC50: 1.8 μM (in U87 cells)
  99.88%
TAK-220        
RANTES-CCR5, IC50: 3.5 nM (in CHO cells)
MIP-1α-CCR5, IC50: 1.4 nM (in CHO cells)
        99.95%
Vicriviroc maleate        
CCR5, Ki: 2.5 nM
        99.91%
BMS CCR2 22  
CCR2, IC50: 5.1 nM
              99.87%
GSK2239633A      
[125I]-TARC-CCR4, pIC50: 7.96
          99.86%
ALK4290    
CCR3, Ki: 3.2 nM
            99.21%
C-021      
CCR4
          99.94%
BI 639667
CCR1, IC50: 1.8 nM (in Ca2+ flux assay)
                99.54%
CCR1 antagonist 9
CCR1, IC50: 6.8 nM (in calcium flux assay)
                99.88%
C-021 dihydrochloride      
CCR4
          ≥99.0%
AZD2423  
CCR2
              98.56%
YM022
CCR1, Ki: 63 nM
CCR2, Ki: 68 pM
              99.0%
CCR2 antagonist 3  
CCR2
              98.10%
Vercirnon sodium                
CCR9, IC50: 10 nM
98.76%
Aplaviroc hydrochloride        
CCR5
        99.76%
Nifeviroc        
CCR5
        98.17%
CCR2 antagonist 4  
CCR2b, IC50: 180 nM
              99.89%
CCR2 antagonist 1  
CCR2, Ki: 2.4 nM
              98.67%
SB-328437    
CCR3, IC50: 4.5 nM
            98.48%
AZD-5672        
CCR5, IC50: 0.32 nM
       
CCR8 antagonist 1              
CCR8, Ki: 1.6 nM
  98.71%
CCR4-351      
CCR4
          98.02%
CCR4-351 hydrochloride      
CCR4
          98.59%
PF-04634817  
Rat CCR2, IC50: 20.8 nM
   
CCR5, IC50: 470 nM
        98.87%
Aplaviroc        
CCR5
       
CCX354
CCR1
                ≥99.0%
RS102895
CCR1, IC50: 17800 nM
CCR2, IC50: 360 nM
             
MK-0812  
CCR2
              99.75%
INCB 3284 dimesylate  
MCP-1-hCCR2, IC50: 3.7 nM
              ≥98.0%
PF-04634817 succinate  
Rat CCR2, IC50: 20.8 nM
   
CCR5, IC50: 470 nM
        ≥99.0%
Fuscin        
CCR5
       
INCB3344 R-isomer  
CCR2
             
BMS-817399
CCR1, IC50: 1 nM
               
CCR8 antagonist 2              
CCR8
 
CCR5 antagonist 1        
CCR5
       
CCR2 antagonist 5  
hCCR2, IC50: 37 nM
mCCR2, Ki: 9.6 μM
             
CKLF1-C27 TFA      
CCR4
         
BMS-639623    
CCR3, IC50: 0.3 nM
           
CCR4 antagonist 3-1      
[125I]-TARC-CCR4, IC50: 1.7 μM
         
CKLF1-C27      
CCR4
         
CCR3 antagonist 1    
CCR3