226226-39-7
226226-39-7
Chemical Structure
CCR2 antagonist 4
Synonym(s): Teijin compound 1
- CAS No.: 226226-39-7
- Formula:C21H21ClF3N3O2
- Molecular Weight:439.86
IUPAC Name: (R)-N-(2-((1-(4-chlorobenzyl)pyrrolidin-3-yl)amino)-2-oxoethyl)-3-(trifluoromethyl)benzamide
InChIKey: BAOQJSULMWXFRK-GOSISDBHSA-N
SMILES: O=C(NCC(N[C@H]1CN(CC2=CC=C(Cl)C=C2)CC1)=O)C3=CC=CC(C(F)(F)F)=C3
Biological Activity: CCR2 antagonist 4 (Teijin compound 1) is a potent and specific CCR2 antagonist, with IC50s of 180 nM for CCR2b. CCR2 antagonist 4 potently inhibits MCP-1-induced chemotaxis with an IC50 of 24 nM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CCR2 antagonist 4 | 100.0% | CCR2 antagonist 4 (Teijin compound 1) is a potent and specific CCR2 antagonist, with IC50s of 180 nM for CCR2b. CCR2 antagonist 4 potently inhibits MCP-1-induced chemotaxis with an IC50 of 24 nM. | ||||||||||||||||||||
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