Viscumneoside V
Viscumneoside V is a plant-derived anti-inflammatory agent present in Viscum album var. coloratum. Viscumneoside V inhibits the expression of MCP-1 and promotes the production of RANTES in LPS-stimulated immune cells. Viscumneoside V can be used for research related to skin rashes.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 98.24%
- CAS No.: 119016-92-1
- Formule: C32H40O19
- Masse moléculaire:728.65
-
Stockage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
Activité biologique
|
CCR2 |
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| BMDC | IC50 |
50 μM
Compound: 12
|
Antiinflammatory activity in C57BL/6 mouse BMDCs assessed as inhibition of LPS-stimulated IL-12p40 production treated 1 hr before LPS challenge measured 18 hrs post stimulation by ELISA
Antiinflammatory activity in C57BL/6 mouse BMDCs assessed as inhibition of LPS-stimulated IL-12p40 production treated 1 hr before LPS challenge measured 18 hrs post stimulation by ELISA
|
[PMID: 23484668] |
Viscumneoside V (1-50 μM; 25 h) potently inhibits MCP-1 production and promotes RANTES production in LPS-stimulated RAW264.7 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Cell Line:LPS-stimulated RAW264.7 murine macrophage cells
-
Concentration:1-50 μM
-
Incubation Time:1 h (pre-incubation); 24 h (LPS stimulation)
-
Result:Significantly suppressed LPS-induced MCP-1 production at all tested concentrations.
Showed dose-dependent reductions.\nSignificantly increased LPS-induced RANTES production at 25, 50 μM.
Showed smaller increases at 1, 5, 10 μM.
Chemical Information
-
CAS No. 119016-92-1
-
Appearance Solid
-
Masse moléculaire 728.65
-
Formule C32H40O19
-
Color Off-white to light yellow
-
SMILES
O=C1C2=C(O)C=C(O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O[C@H]4[C@@H]([C@](O)(CO4)CO[C@H]5[C@@H]([C@](O)(CO5)CO)O)O)C=C2O[C@H](C6=CC(OC)=C(C=C6)O)C1
-
Structure Classification
-
Initial Source
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Pureté et documentation
-
Fiche technique (274 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Instruction de manipulation (2659 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Viscumneoside V Related Classifications
HY-N17908 Related Classifications
Powered by Bioz