Viscumneoside V

Cat. No.: HY-N17908 Purity: 98.24%: Data Sheet
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Viscumneoside V is a plant-derived anti-inflammatory agent present in Viscum album var. coloratum. Viscumneoside V inhibits the expression of MCP-1 and promotes the production of RANTES in LPS-stimulated immune cells. Viscumneoside V can be used for research related to skin rashes.

For research use only. We do not sell to patients.

Viscumneoside V Chemical Structure

CAS No. : 119016-92-1

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CCR1 CCR2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9

Biological Activity
Purity & Documentation
References
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Description

IC₅₀ & Target^[1]

CCR2

In Vitro

Viscumneoside V (1-50 μM; 25 h) potently inhibits MCP-1 production and promotes RANTES production in LPS-stimulated RAW264.7 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

ELISA Assay^[1]

Cell Line:	LPS-stimulated RAW264.7 murine macrophage cells
Concentration:	1-50 μM
Incubation Time:	1 h (pre-incubation); 24 h (LPS stimulation)
Result:	Significantly suppressed LPS-induced MCP-1 production at all tested concentrations. Showed dose-dependent reductions.\nSignificantly increased LPS-induced RANTES production at 25, 50 μM. Showed smaller increases at 1, 5, 10 μM.

Molecular Weight

728.65

Formula

C₃₂H₄₀O₁₉

CAS No.

119016-92-1

Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C1C2=C(O)C=C(O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O[C@H]4[C@@H]([C@](O)(CO4)CO[C@H]5[C@@H]([C@](O)(CO5)CO)O)O)C=C2O[C@H](C6=CC(OC)=C(C=C6)O)C1

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation

Purity: 98.24%

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Data Sheet (274 KB) SDS (252 KB)

COA (255 KB) HNMR (151 KB) RP-HPLC (182 KB)

Handling Instructions (2659 KB)

References

[1]. Choi HJ, et al. Selective Immune Modulating Activities of Viscum album and Its Components; A Possibility of Therapeutics on Skin Rash Induced by EGFR Inhibitors. Integr Cancer Ther. 2022;21:15347354221118332. [Content Brief]

Viscumneoside V Related Classifications

Inflammation/Immunology

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Viscumneoside V119016-92-1CCRCC chemokine receptorerlotinib-induced skin rashimmune cellsRAW264.7 cellsmacrophageLPSRANTESMCP-1Viscum album var. coloratumInhibitorinhibitorinhibit

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