2. Protein Tyrosine Kinase/RTK
  3. Insulin Receptor
  4. Insulin solution (human)

Insulin solution (human) is a polypeptide hormone that regulates the level of glucose. Insulin solution (human) can be used for the diabetes mellitus.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

CAS No. : 11061-68-0

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Customer Review

Based on 92 publication(s) in Google Scholar

Other Forms of Insulin solution (human):

Insulin solution (human) Related Antibodies

Top Publications Citing Use of Products

92 Publications Citing Use of MCE Insulin solution (human)

IF
Bio/Physico-chemical Assay
WB

    Insulin solution (human) purchased from MedChemExpress. Usage Cited in: Signal Transduct Target Ther. 2025 Nov 4;10(1):361.  [Abstract]

    Tissues from GIST patient samples were digested and resuspended in GIST primary cell culture medium, 1% Anti-Anti, 50 ng/mL SCF, 125 ng/mL EGF, 20 ng/mL bFGF (HY-P7004), 25 ng/mL Hydrocortisone (HY-N0583), and 5 µg/mL Insulin. Olverembatinib inhibited lipid droplet accumulation and lipid uptake in SDH-deficient GIST primary cells and downregulated CD36 in primary SDH-deficient GIST cells..

    Insulin solution (human) purchased from MedChemExpress. Usage Cited in: Signal Transduct Target Ther. 2025 Nov 4;10(1):361.  [Abstract]

    Tissues from GIST patient samples were digested and resuspended in GIST primary cell culture medium, 1% Anti-Anti, 50 ng/mL SCF, 125 ng/mL EGF, 20 ng/mL bFGF (HY-P7004), 25 ng/mL Hydrocortisone (HY-N0583), and 5 µg/mL Insulin. Olverembatinib inhibited lipid droplet accumulation and lipid uptake in SDH-deficient GIST primary cells and downregulated CD36 in primary SDH-deficient GIST cells.

    Insulin solution (human) purchased from MedChemExpress. Usage Cited in: Theranostics. 2022 Nov 7;12(18):7699-7716.  [Abstract]

    For insulin tolerance tests, mice on HFD for 15 weeks received an intraperitoneal injection of Insulin (1.0 U/kg body weight) after 6 hours of fasting. Glucose level was measured in tail blood at 0, 15, 30, 60, 90, and 120 mins after glucose or insulin injection using a glucometer.

    Insulin solution (human) purchased from MedChemExpress. Usage Cited in: Theranostics. 2020 Mar 26;10(10):4705-4719.   [Abstract]

    Insulin tolerance tests (ITT) were performed by intraperitoneally injecting Insulin (0.75 unit/kg in 0.9% wt/vol saline) to mice that had been fasted for 6 h. Blood glucose levels were measured at 0, 15, 30, 60, and 120 minutes using an Infinity glucose meter.

    • Biological Activity

    • Purity & Documentation

    • References

    • Customer Review

    Description

    Insulin solution (human) is a polypeptide hormone that regulates the level of glucose. Insulin solution (human) can be used for the diabetes mellitus[1][2].

    In Vivo

    Insulin solution (human) (0.75 U/kg; ip; once) can significantly reduce blood glucose levels in 15 minutes[1].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Animal Model: Slc35d3-Flox mice and Slc35d3-wild type mice injected with 100 mg/mLl D-Glucose (HY-B0389)[1]
    Dosage: 0.75 U/kg
    Administration: ip; once
    Result: Significantly lowers blood glucose levels.
    CAS No.
    Appearance

    Liquid

    Color

    Colorless to light yellow

    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    Store at 4°C, do not freeze
    Solvent & Solubility
    In Vitro: 

    DMSO : 5 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

    • Molarity Calculator

    • Dilution Calculator

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    Mass
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    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start)

    C1

    ×
    Volume (start)

    V1

    =
    Concentration (final)

    C2

    ×
    Volume (final)

    V2

    In Vivo:

    Select the appropriate dissolution method based on your experimental animal and administration route.

    For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
    To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
    The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

    • Protocol 1

      Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

      Solubility: ≥ 0.5 mg/mL; Clear solution

      This protocol yields a clear solution of ≥ 0.5 mg/mL (saturation unknown).

      Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (5.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

      Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
    • Protocol 2

      Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

      Solubility: ≥ 0.5 mg/mL; Clear solution

      This protocol yields a clear solution of ≥ 0.5 mg/mL (saturation unknown).

      Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (5.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

      Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

    Dosage

    mg/kg

    Animal weight
    (per animal)

    g

    Dosing volume
    (per animal)

    μL

    Number of animals

    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
    Please enter your animal formula composition:
    %
    DMSO +
    % 
    +
    %
    Tween-80 +
    %
    Saline
    Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
    The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
    Calculation results:
    Working solution concentration: mg/mL
    Method for preparing stock solution: mg drug dissolved in μL  DMSO (Stock solution concentration: mg/mL).
    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
    Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.
     If the continuous dosing period exceeds half a month, please choose this protocol carefully.
    Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
    Purity & Documentation

    Purity: 95%

    SDS (251 KB)

    COA (231 KB)

    Handling Instructions (2659 KB)
    References
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    Insulin solution (human) Related Classifications

    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Insulin solution (human)11061-68-0Insulin Receptorpolypeptide hormonediabetes mellitusInhibitorinhibitorinhibit

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