1. Recombinant Proteins
  2. Cytokines and Growth Factors
  3. Interleukin & Receptors
  4. IL-1RA IL-2 Receptor
  5. IL-2R alpha
  6. IL-2R alpha/CD25 Protein, Human (191a.a, HEK293, His)

IL-2R alpha/CD25 Protein, Human (191a.a, HEK293, His)

Cat. No.: HY-P7215
Handling Instructions

IL-2R alpha/CD25 Protein, Human (HEK293, His), also known at Tac antigen and a CD25, is a 42 kDa transmembrane protein. The interleukin 2 receptor alpha, beta and gamma chain constitute the high-affinity IL2 receptor.

For research use only. We do not sell to patients.

Protein Expression Service

Recombinant Proteins-MedChemExpress
Size Price Stock Quantity
10 μg $160 In-stock
Estimated Time of Arrival: December 31
50 μg $390 In-stock
Estimated Time of Arrival: December 31
100 μg   Get quote  
250 μg   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Technical Parameters

  • Properties

  • Documentation

Species

Human

Source

HEK 293

Accession

P01589 (L23-C213)

Gene ID

3559

Synonyms
rHuIL-2Rα, His; TAC-antigen; CD25
AA Sequence

LCDDDPPEIPHATFKAMAYKEGTMLNCECKRGFRRIKSGSLYMLCTGNSSHSSWDNQCQCTSSATRNTTKQVTPQPEEQKERKTTEMQSPMQPVDQASLPGHCREPPPWENEATERIYHFVVGQMVYYQCVQGYRALHRGPAESVCKMTHGKTRWTQPQLICTGEMETSQFPGEEKPQASPEGRPESETSC

Molecular Weight

Approximately 42 kDa

Biological Activity
The ED50 is <1.5 μg/mL as measured by murine CTLL-2 cells.
Appearance

Lyophilized powder.

Formulation

Lyophilized after extensive dialysis against PBS.

Endotoxin Level

<0.2 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O or PBS.

Storage & Stability

Stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Background

The cytokine interleukin 2 (IL2) is produced by activated helper T lymphocytes and stimulates proliferation and effector functions of a variety of cells of the immune system. High-affinity IL2 receptors consist of three distinct components, the α chain (IL2Rα, 50-55 kD), the β chain (IL2Rβ, 70-75 kD) and the γ chain[1].

Documentation
References
  • Reconstitution Calculator

  • Dilution Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
IL-2R alpha/CD25 Protein, Human (191a.a, HEK293, His)
Cat. No.:
HY-P7215
Quantity:
MCE Japan Authorized Agent: