1. Recombinant Proteins
  2. Neurotrophin-3 Protein, Human

Neurotrophin-3 Protein, Human

Cat. No.: HY-P70456
Handling Instructions

Neurotrophin-3 Protein, Human is a recombinant Neurotrophin-3 protein expressed in E. coli system. Neurotrophin-3 is widely expressed in the nervous system. Neurotrophin-3 reduces cellular damage, improves neuronal regeneration in different models of lesions[1].

For research use only. We do not sell to patients.

Protein Expression Service

Recombinant Proteins-MedChemExpress
Size Price Stock Quantity
10 μg $340 In-stock
Estimated Time of Arrival: December 31
50 μg $1020 In-stock
Estimated Time of Arrival: December 31
100 μg   Get quote  
250 μg   Get quote  

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  • Technical Parameters

  • Properties

  • Documentation

Synonyms
Neurotrophin-3; NT-3; HDNF; Nerve Growth Factor 2; NGF-2; Neurotrophic Factor; NTF3
Species

Human

Source

E. coli

Accession

P20783 (Y139-T257)

Gene ID

4908

Molecular Weight

Approximately 14.0 kDa

AA Sequence

YAEHKSHRGEYSVCDSESLWVTDKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTSQTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGRT

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Biological Activity
Data is not available.
Appearance

Lyophilized powder.

Formulation

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 250 mM NaCl, pH 7.2.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

Storage & Stability

Stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US;may vary elsewhere.

Background

Neurotrophin‐3 (NT‐3), a trophic factor from the neurotrophin family, is widely expressed in the nervous system.
The physiological actions of NT‐3 are mediated by the activation of two membrane receptors: the low‐affinity receptor p75 and the high‐affinity receptor Trk. NT‐3 activates the TrkC receptor and binds with less affinity to TrkB and TrkA.
NT‐3 reduces cellular damage, improves neuronal regeneration in different models of lesions or neurodegeneration, and participates in synaptic reorganization, synapse formation, and neuronal plasticity[1].

Documentation
References
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Product Name:
Neurotrophin-3 Protein, Human
Cat. No.:
HY-P70456
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