2. PROTAC
  3. PROTAC Linkers
  4. HS-PEG5-CH2CH2NH2 hydrochloride

HS-PEG5-CH2CH2NH2 hydrochloride  (Synonyms: Thiol-PEG5-amine hydrochloride)

Cat. No.: HY-130872A Purity: ≥98.0%
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HS-PEG5-CH2CH2NH2 hydrochloride is a PROTAC linker and belongs to the PEG class. Can be used to synthesize PROTAC molecules.

For research use only. We do not sell to patients.

HS-PEG5-CH2CH2NH2 hydrochloride Chemical Structure

HS-PEG5-CH2CH2NH2 hydrochloride Chemical Structure

CAS No. : 1446256-16-1

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5 mg USD 100 In-stock
10 mg USD 160 In-stock
25 mg USD 320 In-stock
50 mg USD 510 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of HS-PEG5-CH2CH2NH2 hydrochloride:

HS-PEG5-CH2CH2NH2 hydrochloride Related Antibodies

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Description

HS-PEG5-CH2CH2NH2 hydrochloride is a PROTAC linker and belongs to the PEG class. Can be used to synthesize PROTAC molecules.

Molecular Weight

333.87

Formula

C12H28ClNO5S
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

SCCOCCOCCOCCOCCOCCN.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 250 mg/mL (748.79 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9952 mL 14.9759 mL 29.9518 mL
5 mM 0.5990 mL 2.9952 mL 5.9904 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9952 mL 14.9759 mL 29.9518 mL 74.8794 mL
5 mM 0.5990 mL 2.9952 mL 5.9904 mL 14.9759 mL
10 mM 0.2995 mL 1.4976 mL 2.9952 mL 7.4879 mL
15 mM 0.1997 mL 0.9984 mL 1.9968 mL 4.9920 mL
20 mM 0.1498 mL 0.7488 mL 1.4976 mL 3.7440 mL
25 mM 0.1198 mL 0.5990 mL 1.1981 mL 2.9952 mL
30 mM 0.0998 mL 0.4992 mL 0.9984 mL 2.4960 mL
40 mM 0.0749 mL 0.3744 mL 0.7488 mL 1.8720 mL
50 mM 0.0599 mL 0.2995 mL 0.5990 mL 1.4976 mL
60 mM 0.0499 mL 0.2496 mL 0.4992 mL 1.2480 mL
80 mM 0.0374 mL 0.1872 mL 0.3744 mL 0.9360 mL
100 mM 0.0300 mL 0.1498 mL 0.2995 mL 0.7488 mL
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HS-PEG5-CH2CH2NH2 hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HS-PEG5-CH2CH2NH21446256-16-1Thiol-PEG5-aminePROTAC LinkersInhibitorinhibitorinhibit

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