1. Metabolic Enzyme/Protease
    PROTAC
    GPCR/G Protein
  2. Endogenous Metabolite
    PROTAC Linker
    Leukotriene Receptor
  3. Leukotriene B4

Leukotriene B4 (Synonyms: LTB4; 5(S),12(R)-DiHETE)

Cat. No.: HY-107608
Handling Instructions

Leukotriene B4 (LTB4) is known as one of the most potent chemoattractants and activators of leukocytes and is involved in inflammatory diseases. Leukotriene B4 is also an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

Leukotriene B4 Chemical Structure

Leukotriene B4 Chemical Structure

CAS No. : 71160-24-2

Size Price Stock Quantity
25 μg (297.2 µM * 250 μL in Ethanol) USD 585 In-stock
Estimated Time of Arrival: December 31

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Based on 1 publication(s) in Google Scholar

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Description

Leukotriene B4 (LTB4) is known as one of the most potent chemoattractants and activators of leukocytes and is involved in inflammatory diseases. Leukotriene B4 is also an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1][2][3].

IC50 & Target

Alkyl-Chain

 

Human Endogenous Metabolite

 

In Vitro

Leukotriene B4 induces recruitment and activation of neutrophils, monocytes and eosinophils. It also stimulates the production of a number of proinflammatory cytokines and mediators indicating an ability to augment and prolong tissue inflammation[2].
Leukotriene B4 is a pro-inflammatory mediator synthesised in myeloid cells from arachidonic acid[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

336.47

Formula

C₂₀H₃₂O₄

CAS No.
SMILES

CCCCC/C=C\C[[email protected]@H](O)/C=C/C=C/C=C\[[email protected]@H](O)CCCC(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Solution, -20°C, 2 years

References

Purity: ≥98.0%

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Keywords:

Leukotriene B4LTB4 5(S),12(R)-DiHETELeukotriene B 4Leukotriene B-4LTB 4LTB-4Endogenous MetabolitePROTAC LinkerLeukotriene ReceptorInhibitorinhibitorinhibit

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Product Name:
Leukotriene B4
Cat. No.:
HY-107608
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