1. Metabolic Enzyme/Protease
    PROTAC
  2. Endogenous Metabolite
    PROTAC Linker
  3. Leukotriene B4

Leukotriene B4 (Synonyms: LTB4; 5(S),12(R)-DiHETE)

Cat. No.: HY-107608
Handling Instructions

Leukotriene B4 is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

Leukotriene B4 Chemical Structure

Leukotriene B4 Chemical Structure

CAS No. : 71160-24-2

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Description

Leukotriene B4 is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

Alkyl-Chain

 

Human Endogenous Metabolite

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Molecular Weight

336.47

Formula

C₂₀H₃₂O₄

CAS No.

71160-24-2

SMILES

CCCCC/C=C\C[[email protected]@H](O)/C=C/C=C/C=C\[[email protected]@H](O)CCCC(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

Leukotriene B4LTB45(S),12(R)-DiHETELeukotriene B 4Leukotriene B-4LTB 4LTB-4Endogenous MetabolitePROTAC LinkerInhibitorinhibitorinhibit

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Leukotriene B4
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