Leukotriene B4-d4
Based on 1 Customer Validation
Leukotriene B4-d4 is the deuterium labeled Leukotriene B4. Leukotriene B4 (LTB4) is known as one of the most potent chemoattractants and activators of leukocytes and is involved in inflammatory diseases. Leukotriene B4 is also an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
The product specifications provided below refer solely to the active content of Leukotriene B4-d4.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 99.14%
- No. CAS: 124629-74-9
- Fòrmula: C20H28D4O4
- Peso molecular:340.49
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Almacenamiento:
Solution, -20°C, 2 years
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Actividad biológica
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Chemical Information
- Pureza y Documentación
- Referencias
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Help & FAQs
Ver todos los productos específicos de isoformas Endogenous Metabolite
MoreVer todos los productos específicos de isoformas PROTAC Linkers
MoreVer todos los productos específicos de isoformas Leukotriene Receptor
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Actividad biológica
Descripciòn
The product specifications provided below refer solely to the active content of Leukotriene B4-d4.
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Aplicación
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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No. CAS 124629-74-9
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Unlabeled CAS 71160-24-2
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Appearance Liquid
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Peso molecular 340.49
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Fòrmula C20H28D4O4
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Color Colorless to light yellow
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SMILES
CCCCC/C([2H])=C([2H])\C[C@@H](O)/C=C/C=C/C([2H])=C([2H])\[C@@H](O)CCCC(O)=O
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Synonyms
LTB4-d4; 5(S),12(R)-DiHETE-d4
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Solution, -20°C, 2 years
Pureza y Documentación
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Ficha de datos (274 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Leukotriene B4-d4 Related Classifications
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