2. Lipids
  3. Isotope-Labeled Lipids
  4. Isotope-Labeled Eicosanoids

Isotope-Labeled Eicosanoids

 

Isotope-Labeled Eicosanoids (62):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-101952S
    Prostaglandin E2-d4 34210-10-1 99.90%
    Prostaglandin E2-d4 is the deuterium labeled Prostaglandin E2. Prostaglandin E2 (PGE2) is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation.
    Prostaglandin E2-d<sub>4</sub>
  • HY-12956S
    Dinoprost-d4 34210-11-2 99.9%
    Dinoprost-d4 is the deuterium labeled Dinoprost. Dinoprost (Prostaglandin F2α) is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist. Dinoprost is a luteolytic hormone produced locally in the endometrial luminal epithelium and corpus luteum (CL). Dinoprost plays a key role in the onset and progression of labour.
    Dinoprost-d<sub>4</sub>
  • HY-15598S
    20-HETE-d6 2548939-89-3 99.9%
    20-HETE-d6 is the deuterium labeled 20-HETE.
    20-HETE-d<sub>6</sub>
  • HY-107608S
    Leukotriene B4-d4 124629-74-9 99.14%
    Leukotriene B4-d4 is the deuterium labeled Leukotriene B4. Leukotriene B4 (LTB4) is known as one of the most potent chemoattractants and activators of leukocytes and is involved in inflammatory diseases. Leukotriene B4 is also an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
    Leukotriene B4-d<sub>4</sub>
  • HY-101988S
    Prostaglandin D2-d4 211105-29-2 98.81%
    Prostaglandin D2-d4 is the deuterium labeled Prostaglandin D2. Prostaglandin D2 (PGD2) is one of the major PGs actively produced in the brain of various mammals. Prostaglandin D2 is one of the most potent endogenous sleep promoting substances. PGD2 plays a protective role by suppressing inflammation.
    Prostaglandin D2-d<sub>4</sub>
  • HY-113446S
    Leukotriene C4-d5 1441421-73-3
    Leukotriene C4-d5 is the deuterium labeled Leukotriene C4. Leukotriene C4 is the parent cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione to LTA4.
    Leukotriene C4-d<sub>5</sub>
  • HY-113439S
    12-HETE-d8 2525175-25-9 98.03%
    12-HETE-d8 is the deuterium labeled 12-HETE. 12-HETE, a major metabolic product of arachidonic acid using 12-LOX catalysis, inhibits cell apoptosis in a dose-dependent manner. 12-HETE promotes the activation and nuclear translocation of NF-κB through the integrin-linked kinase (ILK) pathway.12-HETE has both anti-thrombotic and pro-thrombotic effects. 12-HETE is a neuromodulator.
    12-HETE-d<sub>8</sub>
  • HY-114988S
    tetranor-PGEM-d6 1240398-16-6 99.9%
    tetranor-PGEM-d6 is the deuterium labeled tetranor-PGEM.
    tetranor-PGEM-d<sub>6</sub>
  • HY-113434S
    5(S)-HETE-d8 330796-62-8
    5(S)-HETE-d8 is the deuterium labeled 5(S)-HETE.
    5(S)-HETE-d<sub>8</sub>
  • HY-130494S
    (±)11(12)-EET-d11 2699607-19-5 98.0%
    (±)11(12)-EET-d11 is the deuterium labeled (±)11(12)-EET. (±)11(12)-EET is a NLRP3 inflammasome inhibitor. (±)11(12)-EET can be used for the research of anti-inflammatory, angiogenic and cardioprotective.
    (±)11(12)-EET-d<sub>11</sub>
  • HY-113358S
    6-keto Prostaglandin F1α-d4 82414-64-0 99.9%
    6-keto Prostaglandin F1α-d4 is the deuterium labeled 6-keto Prostaglandin F1α.
    6-keto Prostaglandin F1α-d<sub>4</sub>
  • HY-113209S
    8-Isoprostaglandin F2α-d4 211105-40-7 98.41%
    8-Iso-PGF2a-d4 (8-iso Prostaglandin F2α-d4) is an active compound. 8-Iso-PGF2a-d4 can be used the internal standard.
    8-Isoprostaglandin F2α-d<sub>4</sub>
  • HY-113465S
    Leukotriene E4-d5 1240398-14-4 98.5%
    Leukotriene E4-d5 is the deuterium labeled Leukotriene E4. Leukotriene E4 (LTE4) is produced by the action of dipeptidase on LTD4. Leukotriene E4 is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A). Leukotriene E4 accumulates in both plasma and urine and urinary excretion of Leukotriene E4 is most often used as an indicator of asthma.
    Leukotriene E4-d<sub>5</sub>
  • HY-108568S
    15-Deoxy-Δ-12,14-prostaglandin J2-d4 1542166-82-4 98.10%
    15-Deoxy-Δ-12,14-prostaglandin J2-d4 is the deuterium labeled 15-Deoxy-Δ-12,14-prostaglandin J2. 15-Deoxy-Δ-12,14-prostaglandin J2 (15d-PGJ2) is a cyclopentenone prostaglandin and a metabolite of PGD2. 15-Deoxy-Δ-12,14-prostaglandin J2 is a selective PPARγ (EC50 of 2 μM) and a covalent PPARδ agonist. 15-Deoxy-Δ-12,14-prostaglandin J2 promotes efficient differentiation of C3H10T1/2 fibroblasts to adipocytes with an EC50 of 7 μM.
    15-Deoxy-Δ-12,14-prostaglandin J2-d<sub>4</sub>
  • HY-113456S
    Leukotriene D4-d5 1240398-17-7 98.4%
    Leukotriene D4-d5 is the deuterium labeled Leukotriene D4. Leukotriene D4 is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) produced by the metabolism of LTC4 by γ-glutamyl transpeptidase. Leukotriene D4 is the first cysteinyl-leukotriene metabolite of LTC4. Leukotriene D4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute hypersensitivity.
    Leukotriene D4-d<sub>5</sub>
  • HY-113420S
    11-Dehydro-thromboxane B2-d4 1240398-15-5 99.9%
    11-Dehydro-thromboxane B2-d4 is the deuterium labeled 11-Dehydro-thromboxane B2.
    11-Dehydro-thromboxane B2-d<sub>4</sub>
  • HY-101952S1
    Prostaglandin E2-d9 1356347-42-6 99.5%
    Prostaglandin E2-d9 is the deuterium labeled Prostaglandin E2. Prostaglandin E2 (PGE2) is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation.
    Prostaglandin E2-d<sub>9</sub>
  • HY-101988S1
    Prostaglandin D2-d9 2254642-52-7 99.9%
    Prostaglandin D2-d9 is the deuterium labeled Prostaglandin D2. Prostaglandin D2 (PGD2) is one of the major PGs actively produced in the brain of various mammals. Prostaglandin D2 is one of the most potent endogenous sleep promoting substances. PGD2 plays a protective role by suppressing inflammation.
    Prostaglandin D2-d<sub>9</sub>
  • HY-113254S1
    13,14-Dihydro-15-keto-PGE2-d9 2750534-81-5 99.9%
    13,14-Dihydro-15-keto-PGE2-d9 is the deuterium labeled 13,14-Dihydro-15-keto-PGE2.
    13,14-Dihydro-15-keto-PGE2-d<sub>9</sub>
  • HY-113336S
    15(S)-HETE-d8 84807-87-4 98.1%
    15(S)-HETE-d8 is the deuterium labeled 15(S)-HETE.
    15(S)-HETE-d<sub>8</sub>