1240398-17-7
Chemical Structure
Leukotriene D4-d5
- CAS No.: 1240398-17-7
- Formula:C25H35D5N2O6S
- Molecular Weight:501.69
IUPAC Name: (5S,6R,7E,9E,11Z,14Z)-6-(((R)-2-amino-3-((carboxymethyl)amino)-3-oxopropyl)thio)-5-hydroxyicosa-7,9,11,14-tetraenoic-19,19,20,20,20-d5 acid
InChIKey: YEESKJGWJFYOOK-HXHZKDJLSA-N
SMILES: N[C@@H](CS[C@H](/C=C/C=C/C=C\C/C=C\CCCC([2H])(C([2H])([2H])[2H])[2H])[C@H](CCCC(O)=O)O)C(NCC(O)=O)=O
Biological Activity: Leukotriene D4-d5 is the deuterium labeled Leukotriene D4. Leukotriene D4 is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) produced by the metabolism of LTC4 by γ-glutamyl transpeptidase. Leukotriene D4 is the first cysteinyl-leukotriene metabolite of LTC4. Leukotriene D4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute hypersensitivity.
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Leukotriene D4-d5 | Leukotriene D4-d5 is the deuterium labeled Leukotriene D4. Leukotriene D4 is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) produced by the metabolism of LTC4 by γ-glutamyl transpeptidase. Leukotriene D4 is the first cysteinyl-leukotriene metabolite of LTC4. Leukotriene D4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute hypersensitivity. | |||||||||||||||||||||
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Leukotriene D4 | 98.5% | Leukotriene D4 is a potent bronchoconstrictor. Leukotriene D4 has the potential for the research of asthma. Leukotriene D4 induces edema and increases capillary permeability. | ||||||||||||||||||||
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Keywords
