1. Metabolic Enzyme/Protease
  2. Drug Metabolite
    Endogenous Metabolite
  3. Leukotriene D4

Leukotriene D4 

Cat. No.: HY-113456 Purity: ≥98.0%
COA Handling Instructions

Leukotriene D4 is a potent bronchoconstrictor. Leukotriene D4 has the potential for the research of asthma. Leukotriene D4 induces edema and increases capillary permeability.

For research use only. We do not sell to patients.

Leukotriene D4 Chemical Structure

Leukotriene D4 Chemical Structure

CAS No. : 73836-78-9

Size Price Stock Quantity
Solution
10 μg (201.34 µM * 100 μL in Ethanol) USD 220 In-stock
Estimated Time of Arrival: December 31
Solution
50 μg (201.34 µM * 500 μL in Ethanol) USD 850 In-stock
Estimated Time of Arrival: December 31

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Leukotriene D4:

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  • Biological Activity

  • Purity & Documentation

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Description

Leukotriene D4 is a potent bronchoconstrictor. Leukotriene D4 has the potential for the research of asthma. Leukotriene D4 induces edema and increases capillary permeability[1][2].

IC50 & Target

Human Endogenous Metabolite

 

In Vivo

Leukotriene D4 (1.5, 3, 6, 12, 24 µg/paw; injected intradermally) causes edema and increases capillary permeability in a dose-related manner in mouse[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 21-24 g, Balb/c male mice[2]
Dosage: 1.5, 3, 6, 12, 24 µg/paw
Administration: Injected intradermally (10 µL was injected into the left hind paw)
Result: Caused significant edematous response and dye extravasation at doses of 1.5-6 ~g/paw.
Clinical Trial
Molecular Weight

496.66

Formula

C25H40N2O6S

CAS No.
SMILES

O=C(O)CNC([[email protected]](CS[[email protected]@H]([[email protected]@H](O)CCCC(O)=O)/C=C/C=C/C=C\C/C=C\CCCCC)N)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Solution, -20°C, 2 years

Purity & Documentation

Purity: ≥98.0%

References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Leukotriene D4
Cat. No.:
HY-113456
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