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Cat. No.: HY-113456S

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Leukotriene D4-d₅

Leukotriene D4-d₅ is the deuterium labeled Leukotriene D4. Leukotriene D4 is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) produced by the metabolism of LTC4 by γ-glutamyl transpeptidase. Leukotriene D4 is the first cysteinyl-leukotriene metabolite of LTC4. Leukotriene D4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute hypersensitivity.

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CAS No.: 1240398-17-7
화학식: C₂₅H₃₅D₅N₂O₆S
분자량:501.69

보관:

Solution, -20°C, 2 years

Leukotriene D4-d₅ Chemical Structure

CAS No.: 1240398-17-7

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
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Biological Activity

제품 설명

All Endogenous Metabolite Isoforms :

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

신청

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS No. 1240398-17-7
Unlabeled Cas 73836-78-9
Appearance Liquid
분자량 501.69
화학식 C₂₅H₃₅D₅N₂O₆S
Color Colorless to light yellow
SMILES

N[C@@H](CS[C@H](/C=C/C=C/C=C\C/C=C\CCCC([2H])(C([2H])([2H])[2H])[2H])[C@H](CCCC(O)=O)O)C(NCC(O)=O)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Solution, -20°C, 2 years

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (263 KB)
SDS (251 KB)
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COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration _(final) Concentration _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
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- In Vitro
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Leukotriene D4-d₅

Leukotriene C4-d5

Leukotriene B4-d4

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Leukotriene D4-d5

Leukotriene C4-d5

Leukotriene B4-d4

All Endogenous Metabolite Isoforms

Biological Activity

Chemical Information

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References

Calculators

Help & FAQs

Leukotriene D4-d5 Related Classifications

HY-113456S Related Classifications

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Leukotriene D4-d₅

Leukotriene D4-d₅ Related Classifications