Isotope-Labeled Lipoxins
Lipoxin A4-d5
Cat. No.: HY-113509S
CAS No.: 1622429-53-1
Synonyms: LXA4-d5
- Formula: C20H27D5O5
- Molecular Weight: 357.50
Lipoxin A4-d5 is the deuterium labeled Lipoxin A4. Lipoxin A4 (LXA4), an endogenous lipoxygenase-derived eicosanoid mediator, has potent dual pro-resolving and anti-inflammatory properties. Lipoxin A4 inhibits proliferation and inflammatory cytokine/chemokine production of human epidermal keratinocytes (NHEKs) associated with the ERK1/2 and NF-kB pathways. Lipoxin A4 inhibits serum amyloid A (SAA)-mediated IL-8 release with an IC50 value of 25.74 nM.
