1. Anti-infection
    Autophagy
  2. HIV
    Autophagy

Ebselen (Synonyms: SPI-1005; PZ-51; CCG-39161)

Cat. No.: HY-13750 Purity: 99.89%
Handling Instructions

Ebselen is a small-molecule capsid Inhibitor of HIV-1 replication.

For research use only. We do not sell to patients.

Ebselen Chemical Structure

Ebselen Chemical Structure

CAS No. : 60940-34-3

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 66 In-stock
Estimated Time of Arrival: December 31
5 mg USD 60 In-stock
Estimated Time of Arrival: December 31
10 mg USD 84 In-stock
Estimated Time of Arrival: December 31
50 mg USD 168 In-stock
Estimated Time of Arrival: December 31
100 mg USD 288 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Ebselen is a small-molecule capsid Inhibitor of HIV-1 replication. Target: Ebselen is an organoselenium compound, as an inhibitor of HIV-1 capsid CTD dimerization. Ebselen inhibits early viral postentry events of the HIV-1 life cycle by impairing the incoming capsid uncoating process. [1] Ebselen is a non-toxic seleno-organic drug with anti-inflammatory and antioxidant properties. Ebselen is an inhibitor of inositol monophosphatase (IMPase). Ebselen permeates the blood-brain barrier and inhibits endogenous inositol monophosphatase in mouse brain. [2]

Clinical Trial
Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6472 mL 18.2362 mL 36.4724 mL
5 mM 0.7294 mL 3.6472 mL 7.2945 mL
10 mM 0.3647 mL 1.8236 mL 3.6472 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

274.18

Formula

C₁₃H₉NOSe

CAS No.

60940-34-3

SMILES

O=C1N(C2=CC=CC=C2)[Se]C3=C1C=CC=C3

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Purity: 99.89%

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Ebselen
Cat. No.:
HY-13750
Quantity:

Ebselen

Cat. No.: HY-13750