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Verapamil hydrochloride

(Synonyms: (±)-Verapamil hydrochloride; CP-16533-1 hydrochloride)
91 Cited Publications
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Based on 91 publication(s) in Google Scholar

Verapamil hydrochloride ((±)-Verapamil hydrochloride) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil hydrochloride also inhibits CYP3A4. Verapamil hydrochloride has the potential for high blood pressure, heart arrhythmias and angina research.

For research use only. We do not sell to patients.

  • Purity: 99.98%
  • CAS No.: 152-11-4
  • Formula: C27H39ClN2O4
  • Molecular Weight:491.06
  • Storage:

    4°C, sealed storage, away from moisture and light

    * In solvent : -80°C, 1 year; -20°C, 6 months (sealed storage, away from moisture and light)

  • Verapamil hydrochloride Chemical Structure
    Verapamil hydrochloride Chemical Structure
  • Experimental Validation Results for Verapamil hydrochloride
  • Experimental Validation Results for Verapamil hydrochloride
  • Experimental Validation Results for Verapamil hydrochloride
  • Experimental Validation Results for Verapamil hydrochloride
  • Experimental Validation Results for Verapamil hydrochloride
  • Experimental Validation Results for Verapamil hydrochloride
CAS No.: 152-11-4
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Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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  • Verapamil hydrochloride Chemical Structure
    Verapamil hydrochloride Chemical Structure
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    Verapamil hydrochloride purchased from MedChemExpress. Usage Cited in: Adv Funct Mater. 2025 May 5.

    Customer Validation
     Cytosolic Ca2+ fluorescence images of BMSCs before and after inhibition of L-type calcium channels with Verapamil (10 μmol/L).

  • 1/16

    Verapamil hydrochloride purchased from MedChemExpress. Usage Cited in: Adv Funct Mater. 2025 May 15.

    Customer Validation
     Verapamil (20 μM; 5 days). Western blotting of ERK and P-ERK levels in NSCs of the Control, Nanoelectrode+MF with Verapamil, and Nanoelectrode+MF groups.

  • 1/16

    Verapamil hydrochloride purchased from MedChemExpress. Usage Cited in: Free Radic Biol Med. 2024 Sep:222:229-243. [Abstract]

    Customer Validation
     HT1080 cells were pretreated with Verapamil (20 μM) or MK-571 sodium for 2 h and then treated with DMSO or RU486 together with concentration gradient of RSL3 for 24 h. Cell viability was measured by CCK-8.

  • 1/16

    Verapamil hydrochloride purchased from MedChemExpress. Usage Cited in: Neurochem Res. 2023 May;48(5):1424-1437. [Abstract]

    Customer Validation
     LPS-stimulated proinflammatory cytokine (IL-1β, IL-6, and TNF-α) expression and extracellular secretion in primary astrocytes are suppressed following administration of the P-gp inhibitor Verapamil (Ver; 70 μM).

  • 1/16

    Verapamil hydrochloride purchased from MedChemExpress. Usage Cited in: Bioact Mater. 2021 Apr 21;6(11):4073-4082. [Abstract]

    Customer Validation
     Intracellular calcium fluorescence staining of MC3T3-E1 cells on day 1 in a blank and samples inhibited by Verapamil (10 μmol/L, 24 h) or SKF-96365 (10 μmol/L, 24 h).

  • 1/16

    Verapamil hydrochloride purchased from MedChemExpress. Usage Cited in: Br J Pharmacol. 2021 Oct;178(20):4155-4175. [Abstract]

    Customer Validation
     Verapamil (Ver; 100 µM; 24 h). Effect of NaHS on neuronal viability against OGD/R injury in vitro. Cell viability was measured by CCK-8 at 24 h post-reoxygenation.

  • Verapamil hydrochloride