1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. Calcium Channel
  3. Ionomycin calcium

Ionomycin calcium (Synonyms: SQ23377 (calcium))

Cat. No.: HY-13434A
Handling Instructions

Ionomycin (calcium) is a Calcium ionophore and an antibiotic produced by Streptomyces conglobatus.

For research use only. We do not sell to patients.

Ionomycin calcium Chemical Structure

Ionomycin calcium Chemical Structure

CAS No. : 56092-82-1

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Ionomycin (calcium) is a Calcium ionophore and an antibiotic produced by Streptomyces conglobatus.

IC50 & Target

Calcium channel[1].

In Vitro

Ionomycin is a Calcium ionophore and an antibiotic produced by Streptomyces conglobatus[1]. Addition of 2 μM Ionomycin to LCLC 103H cells causes an instantaneous increase in intracellular Ca2+ concentration from 50 to 180 nM. DNA and protein analysis in Ionomycin-treated cultures revealed DNA fragmentation and PARP cleavage to an 85-kDa fragment typical of caspase-mediated apoptosis. Necrosis could be detected in ~1-5% of the Ionomycin treated cells as supported by simultaneously positive fluorescein labeling and propidium iodide uptake. Caspase activation in whole cells was followed by monitoring the increase in activity against Ac-DEVD-amc following Ionomycin treatment[2].

Molecular Weight







Room temperature in continental US; may vary elsewhere


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