1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. TRP Channel
  3. GSK1016790A

GSK1016790A 

Cat. No.: HY-19608 Purity: 97.62%
Handling Instructions

GSK1016790A is a potent transient receptor potential vanilloid 4 (TRPV4) activator.

For research use only. We do not sell to patients.

GSK1016790A Chemical Structure

GSK1016790A Chemical Structure

CAS No. : 942206-85-1

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 121 In-stock
Estimated Time of Arrival: December 31
5 mg USD 84 In-stock
Estimated Time of Arrival: December 31
10 mg USD 144 In-stock
Estimated Time of Arrival: December 31
25 mg USD 300 In-stock
Estimated Time of Arrival: December 31
50 mg USD 540 In-stock
Estimated Time of Arrival: December 31
100 mg USD 900 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 3 publication(s) in Google Scholar

Top Publications Citing Use of Products

Publications Citing Use of MCE GSK1016790A

    GSK1016790A purchased from MCE. Usage Cited in: Acs Biomater Sci Eng. 2019 Nov.

    Protein levels of NFATc1 in nuclei of BMSCs cultured on various surfaces with or without GSK101 and RN-1734.

    GSK1016790A purchased from MCE. Usage Cited in: Acs Biomater Sci Eng. 2019 Nov.

    Effects of TRPV4 on NFATc1 nuclear localization in BMSCs on MNTs. Micrographs stained for NFATc1 of BMSCs cultured for 7d on (A) PT, (B) PT with TRPV4 agonist (GSK101) , (C) TNT-30, (D)TNT-100, (E) TNT-100 with TRPV4 antagonist (RN-1734). Red fluorescence: NFATc1; Blue fluorescence: nucleus.
    • Biological Activity

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    Description

    GSK1016790A is a potent transient receptor potential vanilloid 4 (TRPV4) activator.

    Molecular Weight

    655.61

    Formula

    C₂₈H₃₂Cl₂N₄O₆S₂

    CAS No.

    942206-85-1

    SMILES

    O=C(C1=CC2=CC=CC=C2S1)N[[email protected]](C(N3CCN(C([[email protected]@H](NS(=O)(C4=CC=C(Cl)C=C4Cl)=O)CO)=O)CC3)=O)CC(C)C

    Shipping

    Room temperature in continental US; may vary elsewhere.

    Storage
    Powder -20°C 3 years
      4°C 2 years
    In solvent -80°C 6 months
      -20°C 1 month
    Solvent & Solubility
    In Vitro: 

    DMSO : ≥ 33 mg/mL (50.33 mM)

    *"≥" means soluble, but saturation unknown.

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 1.5253 mL 7.6265 mL 15.2530 mL
    5 mM 0.3051 mL 1.5253 mL 3.0506 mL
    10 mM 0.1525 mL 0.7626 mL 1.5253 mL
    *Please refer to the solubility information to select the appropriate solvent.
    References
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    • Molarity Calculator

    • Dilution Calculator

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    This equation is commonly abbreviated as: C1V1 = C2V2

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    × = ×
    C1   V1   C2   V2

    Keywords:

    GSK1016790ATRP ChannelTransient receptor potential channelsInhibitorinhibitorinhibit

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    Product name:
    GSK1016790A
    Cat. No.:
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