2. Signaling Pathways
  3. Epigenetics
  4. Histone Acetyltransferase
  5. GCN5/PCAF Isoform

GCN5/PCAF

 

GCN5/PCAF Related Products (10):

Cat. No. Product Name Effect Purity
  • HY-N2020
    Anacardic Acid
    		Inhibitor 98.07%
    Anacardic Acid, extracted from cashew nut shell liquid, is a histone acetyltransferase inhibitor, inhibits HAT activity of p300 and PCAF, with IC50s of ∼8.5 μM and ∼5 μM, respectively.
  • HY-107569
    Garcinol
    		Inhibitor 98.85%
    Garcinol, a polyisoprenylated benzophenone harvested from Garcinia indica, exerts anti-cholinesterase properties towards acetyl cholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50s of 0.66 µM and 7.39 µM, respectively.
  • HY-124696
    PU139
    		Inhibitor 98.03%
    PU139 is a potent pan-histone acetyltransferase (HAT) inhibitor.
  • HY-129039
    Butyrolactone 3
    		Inhibitor 99.58%
    Butyrolactone 3 (MB-3) is a specifical small-molecule inhibitor of the histone acetyltransferase Gcn5 (IC50=100 μM), which has a high affinity to the Gcn5 enzyme comparable to that of its natural substrate, histone H3.
  • HY-W013274
    CPTH2
    		Inhibitor 99.79%
    CPTH2 is a potent histone acetyltransferase (HAT) inhibitor.
  • HY-16531
    YF-2
    		Activator 99.44%
    YF-2 is a highly selective, blood-brain-barrier permeable histone acetyltransferase activator, acetylates H3 in the hippocampus, with EC50s of 2.75 μM, 29.04 μM and 49.31 μM for CBP, PCAF, and GCN5, respectively, shows no effect on HDAC.
  • HY-16531A
    YF-2 hydrochloride
    		Activator
    YF-2 hydrochloride is a highly selective, blood-brain-barrier permeable histone acetyltransferase activator, acetylates H3 in the hippocampus, with EC50s of 2.75 μM, 29.04 μM and 49.31 μM for CBP, PCAF, and GCN5, respectively, shows no effect on HDAC.
  • HY-W013274A
    CPTH2 hydrochloride
    		Inhibitor
    CPTH2 hydrochloride is a potent histone acetyltransferase (HAT) inhibitor.
  • HY-146277
    CBP/p300-IN-19
    		Inhibitor
    CBP/p300-IN-19 is a potent p300/CBP HAT inhibitor with IC50s of 1.4, 2.2, >100, >100 µM for p300-HAT, CBP-HAT, PCAF, Myst3, respectively.
  • HY-146277A
    CBP/p300-IN-19 hydrochloride
    		Inhibitor
    CBP/p300-IN-19 hydrochloride is a potent and selective p300/CBP HAT inhibitor with IC50s of 1.4, 2.2, >100, >100 µM for p300-HAT, CBP-HAT, PCAF, Myst3, respectively.