2. Signaling Pathways
  3. Epigenetics
  4. Histone Acetyltransferase
  5. GCN5/PCAF Isoform
  6. GCN5/PCAF Inhibitor

GCN5/PCAF Inhibitor

GCN5/PCAF Inhibitors (8):

Cat. No. Product Name Effect Purity
  • HY-N2020
    Anacardic Acid
    		Inhibitor 98.07%
    Anacardic Acid, extracted from cashew nut shell liquid, is a histone acetyltransferase inhibitor, inhibits HAT activity of p300 and PCAF, with IC50s of ∼8.5 μM and ∼5 μM, respectively.
  • HY-107569
    Garcinol
    		Inhibitor 98.85%
    Garcinol, a polyisoprenylated benzophenone harvested from Garcinia indica, exerts anti-cholinesterase properties towards acetyl cholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50s of 0.66 µM and 7.39 µM, respectively.
  • HY-124696
    PU139
    		Inhibitor 98.03%
    PU139 is a potent pan-histone acetyltransferase (HAT) inhibitor.
  • HY-129039
    Butyrolactone 3
    		Inhibitor 99.58%
    Butyrolactone 3 (MB-3) is a specifical small-molecule inhibitor of the histone acetyltransferase Gcn5 (IC50=100 μM), which has a high affinity to the Gcn5 enzyme comparable to that of its natural substrate, histone H3.
  • HY-W013274
    CPTH2
    		Inhibitor 99.79%
    CPTH2 is a potent histone acetyltransferase (HAT) inhibitor.
  • HY-W013274A
    CPTH2 hydrochloride
    		Inhibitor
    CPTH2 hydrochloride is a potent histone acetyltransferase (HAT) inhibitor.
  • HY-146277
    CBP/p300-IN-19
    		Inhibitor
    CBP/p300-IN-19 is a potent p300/CBP HAT inhibitor with IC50s of 1.4, 2.2, >100, >100 µM for p300-HAT, CBP-HAT, PCAF, Myst3, respectively.
  • HY-146277A
    CBP/p300-IN-19 hydrochloride
    		Inhibitor
    CBP/p300-IN-19 hydrochloride is a potent and selective p300/CBP HAT inhibitor with IC50s of 1.4, 2.2, >100, >100 µM for p300-HAT, CBP-HAT, PCAF, Myst3, respectively.