2592638-13-4
Chemical Structure
CBP/p300-IN-19
- CAS No.: 2592638-13-4
- Formula:C30H27N3O3
- Molecular Weight:477.55
IUPAC Name: 2,3-bis(4-(furan-3-yl)phenyl)-5-(piperidin-4-ylmethoxy)pyrazine
InChIKey: QLCHGDXZIUOABP-UHFFFAOYSA-N
SMILES: C1(C2=CC=C(C3=COC=C3)C=C2)=NC=C(OCC4CCNCC4)N=C1C5=CC=C(C6=COC=C6)C=C5
Biological Activity: CBP/p300-IN-19 is a potent p300/CBP HAT inhibitor with IC50s of 1.4, 2.2, >100, >100 µM for p300-HAT, CBP-HAT, PCAF, Myst3, respectively. CBP/p300-IN-19 shows antitumor activity[1].
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CBP/p300-IN-19 | CBP/p300-IN-19 is a potent p300/CBP HAT inhibitor with IC50s of 1.4, 2.2, >100, >100 µM for p300-HAT, CBP-HAT, PCAF, Myst3, respectively. CBP/p300-IN-19 shows antitumor activity. | |||||||||||||||||||||
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Keywords