1. Epigenetics
  2. Epigenetic Reader Domain
    Histone Acetyltransferase

GSK4028 

Cat. No.: HY-101027A
Handling Instructions

GSK4028 is the enantiomeric negative control of GSK4027, which is a PCAF/GCN5 bromodomain chemical probe, the pIC50 of GSK4028 is 4.9 in a time-resolved fluorescence resonance energy transfer (TR-FRET) assay.

For research use only. We do not sell to patients.

GSK4028 Chemical Structure

GSK4028 Chemical Structure

CAS No. : 2079886-19-2

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 605 In-stock
Estimated Time of Arrival: December 31
5 mg USD 550 In-stock
Estimated Time of Arrival: December 31
10 mg USD 850 In-stock
Estimated Time of Arrival: December 31
25 mg USD 1750 In-stock
Estimated Time of Arrival: December 31
50 mg USD 2750 In-stock
Estimated Time of Arrival: December 31
100 mg USD 3950 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Other Forms of GSK4028:

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

GSK4028 is the enantiomeric negative control of GSK4027, which is a PCAF/GCN5 bromodomain chemical probe, the pIC50 of GSK4028 is 4.9 in a time-resolved fluorescence resonance energy transfer (TR-FRET) assay.

IC50 & Target

pIC50: 4.9 (PCAF/GCN5)[1].

In Vitro

GSK4028 is the enantiomeric negative control of GSK4027, which is a PCAF/GCN5 bromodomain chemical probe, the pIC50 of GSK4028 is 4.9. GSK4028 also demonstrates potency toward BRD4 BD1 and BRD9 inTR-FRET assay with pIC50s of <4.3 and 4.5±0.13, respectively[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6506 mL 13.2528 mL 26.5055 mL
5 mM 0.5301 mL 2.6506 mL 5.3011 mL
10 mM 0.2651 mL 1.3253 mL 2.6506 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

377.28

Formula

C₁₇H₂₁BrN₄O

CAS No.

2079886-19-2

SMILES

BrC1=C(N[[email protected]]2C[[email protected]@H](C3=CC=CC=C3)CN(C)C2)C=NN(C)C1=O

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

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This equation is commonly abbreviated as: C1V1 = C2V2

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Product Name:
GSK4028
Cat. No.:
HY-101027A
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GSK4028

Cat. No.: HY-101027A