1. Epigenetics
  2. Epigenetic Reader Domain

SGC-CBP30 

Cat. No.: HY-15826 Purity: 99.19%
Data Sheet SDS Handling Instructions

SGC-CBP30 is a potent CREBBP/EP300 bromodomain inhibitor with IC50 of 21-69 and 38 nM for CREBBP and EP300 bromodomains, respectively)

For research use only. We do not sell to patients.
SGC-CBP30 Chemical Structure

SGC-CBP30 Chemical Structure

CAS No. : 1613695-14-9

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO $151 In-stock
5 mg $135 In-stock
10 mg $158 In-stock
50 mg $536 In-stock
100 mg $965 In-stock
200 mg   Get quote  
500 mg   Get quote  

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  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

SGC-CBP30 is a potent CREBBP/EP300 bromodomain inhibitor with IC50 of 21-69 and 38 nM for CREBBP and EP300 bromodomains, respectively. IC50 Value: 21-69 nM(for CREBBP); 38 nM(for EP300) Target: Others in vivo: SGC-CBP30 is a highly potent and selective p300/CBP bromodomain inhibitor (IC50 ~0.021-0.069 uM for CBP and ~0.038 uM for p300). It has 40-fold selectivity for CBP over BRD4. It accelerated FRAP recovery at 1 uM. in vivo: N/A

References
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.9645 mL 9.8224 mL 19.6448 mL
5 mM 0.3929 mL 1.9645 mL 3.9290 mL
10 mM 0.1964 mL 0.9822 mL 1.9645 mL
References
Molecular Weight

509.04

Formula

C₂₈H₃₃ClN₄O₃

CAS No.

1613695-14-9

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 31 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
SGC-CBP30
Cat. No.:
HY-15826
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