2229025-70-9
Chemical Structure
WM-3835
- CAS No.: 2229025-70-9
- Formula:C20H17FN2O4S
- Molecular Weight:400.42
IUPAC Name: N'-(4-fluoro-5-methyl-[1,1'-biphenyl]-3-carbonyl)-3-hydroxybenzenesulfonohydrazide
InChIKey: KVJFJJXCBRSCDY-UHFFFAOYSA-N
SMILES: O=C(C1=CC(C2=CC=CC=C2)=CC(C)=C1F)NNS(=O)(C3=CC=CC(O)=C3)=O
Biological Activity: WM-3835 is a potent and high-specific HBO1 (KAT7 or MYST2) inhibitor and binds directly to the acetyl-CoA binding site of HBO1. WM-3835 activates apoptosis while inhibits osteosarcoma (OS) cell proliferation, migration and invasion. WM-3835 has antitumor activity and potently inhibits pOS-1 xenograft growth in mice[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
WM-3835 | 99.78% | WM-3835 is a potent and high-specific HBO1 (KAT7 or MYST2) inhibitor and binds directly to the acetyl-CoA binding site of HBO1. WM-3835 activates apoptosis while inhibits osteosarcoma (OS) cell proliferation, migration and invasion. WM-3835 has antitumor activity and potently inhibits pOS-1 xenograft growth in mice. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
WM-3835 (Standard) | ≥98% | WM-3835 (Standard) is the analytical standard of WM-3835 (HY-134901). This product is intended for research and analytical applications. WM-3835 is a potent and high-specific HBO1 (KAT7 or MYST2) inhibitor and binds directly to the acetyl-CoA binding site of HBO1. WM-3835 activates apoptosis while inhibits osteosarcoma (OS) cell proliferation, migration and invasion. WM-3835 has antitumor activity and potently inhibits pOS-1 xenograft growth in mice. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
-
Similarity Score 0.85
HY-102060WM-8014 -
Similarity Score 0.67
HY-102059MOZ-IN-2 -
Similarity Score 0.62
HY-136473CTX-0124143 -
Similarity Score 0.58
HY-102058RWM-1119 (Standard) -
Similarity Score 0.55
HY-153878BCAT-IN-4 -
Similarity Score 0.54
HY-178522BAS00093476 -
Similarity Score 0.52
HY-115894DapL-IN-1 -
Similarity Score 0.52
HY-145009SN-008 -
Similarity Score 0.52
HY-115462PGN-9856 -
Explore the MedChemAI to find more analogs
