1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Isolithocholic acid

Isolithocholic acid (Synonyms: 3β-Hydroxy-5β-cholanic acid; 3-Epilithocholic acid; β-Lithocholic acid)

Cat. No.: HY-B0172B
Handling Instructions

Isolithocholic acid (β-Lithocholic acid) is an isomer of Lithocholic acid. Isolithocholic acid, a bile acid, is formed by microbial metabolism of Lithocholic acid or Lithocholic acid 3α-sulfate.

For research use only. We do not sell to patients.

Isolithocholic acid Chemical Structure

Isolithocholic acid Chemical Structure

CAS No. : 1534-35-6

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Description

Isolithocholic acid (β-Lithocholic acid) is an isomer of Lithocholic acid. Isolithocholic acid, a bile acid, is formed by microbial metabolism of Lithocholic acid or Lithocholic acid 3α-sulfate[1][2].

IC50 & Target[1]

Microbial Metabolite

 

In Vitro

Isolithocholic acid at 0.01 % does not inhibit spore germination and outgrowth of CF5 and M120, but it significantly inhibits at the higher concentration (0.1 %). Isolithocholic acid (0.00003 %) prevents growth of CD196, M68, CF5, 630, and BI9 and significant decreases strains CF5, BI9, M120, and 630 in toxin activity. Isolithocholic acid (0.0003 %) makes that all strains displays a significant decrease in toxin activity, except for R20291 and M120[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

The levels of fecal Isolithocholic acid shows obvious decreases from day 28 onward in the high fat diet (HFD) group compared with rats fed a normal diet[4].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

376.57

Formula

C₂₄H₄₀O₃

CAS No.
Shipping

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Isolithocholic acid
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HY-B0172B
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